NEPRO Antibody (B-12): sc-376579
- NEPRO Antibody (B-12) is a mouse monoclonal IgG1 κ NEPRO antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 511-547 within an internal region of NEPRO of human origin
- NEPRO Antibody (B-12) is recommended for detection of NEPRO of human origin by WB, IP, IF and ELISA
- Anti-NEPRO Antibody (B-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for NEPRO Antibody (B-12) for WB applications. This reagent is now offered in a bundle with NEPRO Antibody (B-12) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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NEPRO Antibody (B-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects NEPRO protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NEPRO monoclonal antibody (B-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. NEPRO (B-12) antibody recognizes a protein that plays a crucial role in cellular processes, particularly in regulating immune responses and inflammation. NEPRO (B-12) monoclonal antibody targets a protein primarily located in the cytoplasm and involved in signaling pathways that modulate immune cell activity, making NEPRO essential for maintaining homeostasis and responding to pathogens. Dysregulation of NEPRO can lead to various inflammatory diseases and has been implicated in cancer progression, highlighting NEPRO′s importance as a potential therapeutic target. Chromosome 3, where NEPRO gene is located, is known for containing over 1,100 genes, including key tumor suppressor genes and loci associated with various genetic disorders. Understanding NEPRO′s function and implications can provide valuable insights into potential biomarker and therapeutic applications in disease contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
NEPRO Antibody (B-12) References:
- Molecular cytogenetic dissection of human chromosomes 3 and 21 evolution. | Müller, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 206-11. PMID: 10618396
- [New tumor suppressor genes in hot spots of human chromosome 3: new methods of identification]. | Braga, EA., et al. 2003. Mol Biol (Mosk). 37: 194-211. PMID: 12723467
- Plasticity of human chromosome 3 during primate evolution. | Tsend-Ayush, E., et al. 2004. Genomics. 83: 193-202. PMID: 14706448
- Genomic structure and paralogous regions of the inversion breakpoint occurring between human chromosome 3p12.3 and orangutan chromosome 2. | Yue, Y., et al. 2005. Cytogenet Genome Res. 108: 98-105. PMID: 15545721
- Comparative cytogenetics of human chromosome 3q21.3 reveals a hot spot for ectopic recombination in hominoid evolution. | Yue, Y., et al. 2005. Genomics. 85: 36-47. PMID: 15607420
- Evolutionarily plastic regions at human 3p21.3 coincide with tumor breakpoints identified by the 'elimination test'. | Darai, E., et al. 2005. Genomics. 86: 1-12. PMID: 15913951
- The DNA sequence, annotation and analysis of human chromosome 3. | Muzny, DM., et al. 2006. Nature. 440: 1194-8. PMID: 16641997
- Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3. | Nareyeck, G., et al. 2006. Exp Eye Res. 83: 858-64. PMID: 16750193
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NEPRO Antibody (B-12) | sc-376579 | 200 µg/ml | $322.00 | |||
NEPRO Antibody (B-12): m-IgGκ BP-HRP Bundle | sc-523016 | 200 µg Ab, 40 µg BP | $361.00 | |||
NEPRO Antibody (B-12) AC | sc-376579 AC | 500 µg/ml, 25% agarose | $424.00 | |||
NEPRO Antibody (B-12) HRP | sc-376579 HRP | 200 µg/ml | $322.00 | |||
NEPRO Antibody (B-12) FITC | sc-376579 FITC | 200 µg/ml | $336.00 | |||
NEPRO Antibody (B-12) PE | sc-376579 PE | 200 µg/ml | $349.00 | |||
NEPRO Antibody (B-12) Alexa Fluor® 488 | sc-376579 AF488 | 200 µg/ml | $364.00 | |||
NEPRO Antibody (B-12) Alexa Fluor® 546 | sc-376579 AF546 | 200 µg/ml | $364.00 | |||
NEPRO Antibody (B-12) Alexa Fluor® 594 | sc-376579 AF594 | 200 µg/ml | $364.00 | |||
NEPRO Antibody (B-12) Alexa Fluor® 647 | sc-376579 AF647 | 200 µg/ml | $364.00 | |||
NEPRO Antibody (B-12) Alexa Fluor® 680 | sc-376579 AF680 | 200 µg/ml | $364.00 | |||
NEPRO Antibody (B-12) Alexa Fluor® 790 | sc-376579 AF790 | 200 µg/ml | $364.00 | |||
NEPRO (B-12) Neutralizing Peptide | sc-376579 P | 100 µg/0.5 ml | $69.00 |