Neisseria gonorrhoeae Antibody (15804): sc-73449

Neisseria gonorrhoeae Antibody (15804) is a mouse monoclonal IgG2b antibody that detects Neisseria gonorrhoeae with species reactivity in non-specific reactions by enzyme-linked immunosorbent assay (ELISA). Neisseria gonorrhoeae monoclonal antibody (15804) targets a Gram-negative bacterium responsible for the sexually transmitted infection gonorrhea, which primarily colonizes the mucous membranes of the urethra and can spread to other tissues, such as the female endocervix. The ability of Neisseria gonorrhoeae to adhere to nonciliated epithelial cells is facilitated by fimbriae, which play a crucial role in pathogenesis. Additionally, Neisseria gonorrhoeae produces a highly toxic lipopolysaccharide endotoxin and IgA proteases, enhancing virulence and ability to evade the host′s immune response. The presence of these virulence factors is significant as they contribute to the severity of the infection and the challenges in treatment, particularly given the resistance to the penicillin family. Symptoms of gonorrhea include purulent genital discharge and a burning sensation during urination, underscoring the importance of early detection and treatment. Anti-Neisseria gonorrhoeae antibody (15804) is an essential tool for researchers studying this pathogen and its interactions within the host.

The preferred Neisseria gonorrhoeae antibody is Neisseria gonorrhoeae Antibody (4611): sc-57931.