Neisseria gonorrhoeae Antibody (4611): sc-57931

Neisseria gonorrhoeae Antibody (4611) is a mouse monoclonal IgG2b antibody that detects Neisseria gonorrhoeae protein by immunofluorescence (IF). Anti-Neisseria gonorrhoeae antibody (4611) is available as a non-conjugated format. Neisseria gonorrhoeae is a Gram-negative bacterium responsible for the sexually transmitted infection gonorrhea, which primarily colonizes the mucous membranes of the urethra and can spread to other tissues, such as the female endocervix. The bacterium′s ability to adhere to non-ciliated epithelial cells is facilitated by its fimbriae, which play a crucial role in its pathogenesis. Additionally, Neisseria gonorrhoeae produces a highly toxic lipopolysaccharide endotoxin and IgA proteases, enhancing its virulence and ability to evade the host′s immune response. Understanding the structure of Neisseria gonorrhoeae protein is vital, as specific surface structures are essential for interaction with host cells and immune evasion. The presence of these structures not only aids in bacterial attachment but also influences infection severity and host immune response. Common symptoms of gonorrhea include purulent genital discharge and a burning sensation during urination, and notably, Neisseria gonorrhoeae has developed resistance to the penicillin family, making effective treatment increasingly challenging.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Neisseria gonorrhoeae Antibody (4611) References:

1. Emergence of ciprofloxacin resistant Neisseria gonorrhoeae in north India.  |  Sethi, S., et al. 2006. Indian J Med Res. 123: 707-10. PMID: 16873916
2. Neisseria gonorrhoeae PLD directly interacts with Akt kinase upon infection of primary, human, cervical epithelial cells.  |  Edwards, JL. and Apicella, MA. 2006. Cell Microbiol. 8: 1253-71. PMID: 16882030
3. Molecular epidemiology of Neisseria gonorrhoeae in Amsterdam, The Netherlands, shows distinct heterosexual and homosexual networks.  |  Kolader, ME., et al. 2006. J Clin Microbiol. 44: 2689-97. PMID: 16891479
4. Antimicrobial susceptibility of Neisseria gonorrhoeae isolated in Jiangsu Province, China, with a focus on fluoroquinolone resistance.  |  Wang, B., et al. 2006. J Med Microbiol. 55: 1251-1255. PMID: 16914656
5. Neisseria gonorrhoeae DNA recombination and repair enzymes protect against oxidative damage caused by hydrogen peroxide.  |  Stohl, EA. and Seifert, HS. 2006. J Bacteriol. 188: 7645-51. PMID: 16936020
6. Amino acid substitutions in mosaic penicillin-binding protein 2 associated with reduced susceptibility to cefixime in clinical isolates of Neisseria gonorrhoeae.  |  Takahata, S., et al. 2006. Antimicrob Agents Chemother. 50: 3638-45. PMID: 16940068
7. In vitro synergistic effects of double combinations of beta-lactams and azithromycin against clinical isolates of Neisseria gonorrhoeae.  |  Furuya, R., et al. 2006. J Infect Chemother. 12: 172-6. PMID: 16944253
8. Enhancement of antimicrobial activities of cefteram or clavulanic acid/amoxicillin against cefixime-resistant Neisseria gonorrhoeae in the presence of clarithromycin or azithromycin.  |  Onodera, S., et al. 2006. J Infect Chemother. 12: 207-9. PMID: 16944260

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Neisseria gonorrhoeae Antibody (4611) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Neisseria gonorrhoeae Antibody (4611) Specifications

Alternate Product Name: Neisseria gonorrhoeae

Product Clone Name: 4611

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b

Amino Acids:

Epitope Target: Neisseria gonorrhoeae

Epitope Species: Neisseria gonorrhoeae

Product Reactivity/Detection: Neisseria gonorrhoeae

Species Reactivity/Detection: NSR

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF

Vialing Information: Each vial contains 100 µg IgG_2b in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Neisseria gonorrhoeae Antibody (4611): N/A