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NDV HN Antibody (9F7) is a mouse monoclonal IgG1 antibody that detects Newcastle disease virus HN by enzyme-linked immunosorbent assay (ELISA). NDV HN (9F7) antibody recognizes a critical glycoprotein that plays a vital role in the pathogenesis of Newcastle disease, a highly contagious viral infection affecting various avian species. NDV HN is located on the surface of the virus and mediates viral attachment to host cells through interaction with sialic acid-containing receptors. The binding of NDV HN to these receptors facilitates viral entry and triggers cellular responses, including upregulation of TRAIL and death receptors, which are crucial for the host′s immune response. NDV HN is involved in the fusion of viral and cellular membranes, a process regulated by the NDV F protein, enhancing viral infectivity and virulence. NDV HN′s ability to modulate host cell signaling pathways underscores its importance in the viral life cycle and highlights anti-NDV HN antibody (9F7)′s relevance in studying Newcastle disease and developing potential therapeutic strategies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NDV HN Antibody (9F7) | sc-52116 | 100 µg/ml | $316.00 |