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NDV HN Antibody (13H3) is a mouse monoclonal IgG2a antibody that detects Newcastle disease virus HN by enzyme-linked immunosorbent assay (ELISA). NDV HN is a critical glycoprotein that plays a vital role in the pathogenesis of Newcastle disease, a highly contagious viral infection affecting various avian species. NDV HN (13H3) antibody recognizes a protein located on the surface of the virus that is essential for mediating viral attachment to host cells through interaction with sialic acid-containing receptors. The binding of NDV HN to these receptors not only facilitates viral entry but also triggers significant cellular responses, including the upregulation of TRAIL and death receptors, which are crucial for the host′s immune response. NDV HN is involved in the fusion of viral and cellular membranes, a process intricately regulated by the NDV F protein, thereby enhancing viral infectivity and virulence. Anti-NDV HN antibody (13H3) serves as an invaluable tool for researchers studying Newcastle disease virus infection mechanisms and host immune responses, providing insights that could lead to better prevention and treatment strategies for this zoonotic disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NDV HN Antibody (13H3) | sc-52113 | 100 µg/ml | $316.00 |