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NDV HN Antibody (11F12) is a mouse monoclonal IgG2a antibody that detects Newcastle disease virus HN by enzyme-linked immunosorbent assay (ELISA). NDV HN is a critical glycoprotein that plays a vital role in the pathogenesis of Newcastle disease, a highly contagious viral infection affecting various avian species. NDV HN (11F12) antibody recognizes a protein located on the virus surface that is essential for mediating viral attachment to host cells through sialic acid-containing receptors. NDV HN binding to these receptors facilitates viral entry and triggers immunological responses, including TRAIL and death receptor upregulation, which influence host immune response. NDV HN also participates in viral and cellular membrane fusion, a crucial process for virus spread to neighboring cells, enhancing infectivity and virulence. Anti-NDV HN antibody (11F12) serves as an invaluable tool for researchers studying Newcastle disease virus infection mechanisms and host response, providing insights that could lead to better control and prevention strategies for this zoonotic disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NDV HN Antibody (11F12) | sc-52112 | 100 µg/ml | $316.00 |