NDUFA10 Antibody (A-8): sc-376357
- NDUFA10 Antibody (A-8) is a mouse monoclonal IgG1 κ NDUFA10 antibody, cited in 7 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 321-353 near the C-terminus of NDUFA10 of human origin
- NDUFA10 Antibody (A-8) is recommended for detection of NDUFA10 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-NDUFA10 Antibody (A-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for NDUFA10 Antibody (A-8) for WB and IHC(P) applications. These reagents are now offered in bundles with NDUFA10 Antibody (A-8) (see ordering information below).
NDUFA10 Antibody (A-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects NDUFA10 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). anti-NDUFA10 antibody (A-8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. NDUFA10, also known as NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10 or CI-42KD, is a 355 amino acid protein that resides in the mitochondrial matrix, where NDUFA10 serves as an essential accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase complex I. This complex facilitates the transfer of electrons from NADH to the respiratory chain, a process vital for ATP production and overall cellular energy metabolism. NDUFA10 interactions with other proteins within the complex ensure efficient electron transfer and maintain mitochondrial health. Mutations in the genes encoding components of this complex can lead to severe mitochondrial disorders, highlighting NDUFA10′s importance in cellular energy dynamics. The gene encoding NDUFA10 is located on human chromosome 2, which contains over 1,400 genes and represents nearly 8% of the human genome, underscoring NDUFA10′s significance in genetic regulation and potential implications in various diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
NDUFA10 Antibody (A-8) References:
- Human mitochondrial complex I in health and disease. | Smeitink, J. and van den Heuvel, L. 1999. Am J Hum Genet. 64: 1505-10. PMID: 10330338
- Mass spectrometric identification of a novel phosphorylation site in subunit NDUFA10 of bovine mitochondrial complex I. | Schilling, B., et al. 2005. FEBS Lett. 579: 2485-90. PMID: 15848193
- Phosphorylation of B14.5a subunit from bovine heart complex I identified by titanium dioxide selective enrichment and shotgun proteomics. | Pocsfalvi, G., et al. 2007. Mol Cell Proteomics. 6: 231-7. PMID: 17114648
- The phosphorylation pattern of bovine heart complex I subunits. | Palmisano, G., et al. 2007. Proteomics. 7: 1575-83. PMID: 17443843
- Mass spectrometric characterization of mitochondrial complex I NDUFA10 variants. | Muñoz, J., et al. 2008. Proteomics. 8: 1898-908. PMID: 18442173
- Construction and evaluation of a hncDNA library of human 12p transcribed sequences derived from a somatic cell hybrid. | Baens, M., et al. 1993. Genomics. 16: 214-8. PMID: 8486360
- cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. | Loeffen, JL., et al. 1998. Biochem Biophys Res Commun. 253: 415-22. PMID: 9878551
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NDUFA10 Antibody (A-8) | sc-376357 | 200 µg/ml | $316.00 | |||
NDUFA10 Antibody (A-8): m-IgG Fc BP-HRP Bundle | sc-527528 | 200 µg Ab; 10 µg BP | $354.00 | |||
NDUFA10 Antibody (A-8): m-IgG1 BP-HRP Bundle | sc-532901 | 200 µg Ab; 20 µg BP | $354.00 | |||
NDUFA10 Antibody (A-8) AC | sc-376357 AC | 500 µg/ml, 25% agarose | $416.00 | |||
NDUFA10 Antibody (A-8) HRP | sc-376357 HRP | 200 µg/ml | $316.00 | |||
NDUFA10 Antibody (A-8) FITC | sc-376357 FITC | 200 µg/ml | $330.00 | |||
NDUFA10 Antibody (A-8) PE | sc-376357 PE | 200 µg/ml | $343.00 | |||
NDUFA10 Antibody (A-8) Alexa Fluor® 488 | sc-376357 AF488 | 200 µg/ml | $357.00 | |||
NDUFA10 Antibody (A-8) Alexa Fluor® 546 | sc-376357 AF546 | 200 µg/ml | $357.00 | |||
NDUFA10 Antibody (A-8) Alexa Fluor® 594 | sc-376357 AF594 | 200 µg/ml | $357.00 | |||
NDUFA10 Antibody (A-8) Alexa Fluor® 647 | sc-376357 AF647 | 200 µg/ml | $357.00 | |||
NDUFA10 Antibody (A-8) Alexa Fluor® 680 | sc-376357 AF680 | 200 µg/ml | $357.00 | |||
NDUFA10 Antibody (A-8) Alexa Fluor® 790 | sc-376357 AF790 | 200 µg/ml | $357.00 | |||
NDUFA10 (A-8) Neutralizing Peptide | sc-376357 P | 100 µg/0.5 ml | $68.00 |