NAP1L1 Antibody (1E4): sc-57930
- NAP1L1 Antibody (1E4) is a mouse monoclonal IgG1 provided at 500 µl supernatant
- raised against a preparation of yeast proteins UV crosslinked to polyadenylated RNA
- recommended for detection of methylated form of NAP1L1 of mouse, rat, human and y origin by WB and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NAP1L1 Antibody (1E4). This work is in progress.
QUICK LINKS
NAP1L1 Antibody (1E4) is a mouse monoclonal IgG1 antibody that detects the methylated form of NAP1L1, a crucial protein involved in nucleosome assembly, in mouse, rat, and human samples through western blotting (WB) and immunofluorescence (IF) applications. Anti-NAP1L1 antibody (1E4) is available in a non-conjugated form, allowing for versatile experimental use. NAP1L1, also known as nucleosome assembly protein 1-like 1 or NRP, is a 391 amino acid protein that plays a vital role in the regulation of chromatin structure and function. NAP1L1 (1E4) antibody targets a protein primarily localized in the nucleus, where NAP1L1 facilitates the assembly of nucleosomes, thereby compacting DNA into chromatin, which is essential for proper gene expression and DNA replication. NAP1L1 contains acidic domains that are believed to mediate interactions with histones, further underscoring NAP1L1′s importance in chromatin dynamics. Given NAP1L1′s significant role in cell proliferation and potential implications in cancer biology, particularly as a genetic marker for intestinal carcinomas, NAP1L1 is a key player in maintaining genomic stability. With a sequence similarity of 54% to the Saccharomyces cerevisiae Nap1 protein, NAP1L1 is not only critical for nucleosome assembly but also serves as a valuable target for research into chromatin-related processes and their impact on cellular functions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NAP1L1 Antibody (1E4) | sc-57930 | 500 µl supernatant | $322.00 |