NAP1L1 Antibody (2609C3a): sc-81328

NAP1L1 Antibody (2609C3a) is a mouse monoclonal IgG1 antibody that detects NAP1L1 protein of mouse, rat, and human origin by western blotting (WB) and immunoprecipitation (IP). Anti-NAP1L1 antibody (2609C3a) is available as a non-conjugated format. NAP1L1, also known as nucleosome assembly protein 1-like 1, is a crucial nuclear protein consisting of 391 amino acids that plays a significant role in nucleosome assembly and chromatin formation. NAP1L1 is localized in the nucleus and is expressed throughout various tissues in the body, highlighting NAP1L1′s importance in cellular processes. NAP1L1 contains specific acidic domains that facilitate interaction with histones, which is vital for proper nucleosome assembly and, consequently, for the regulation of gene expression. NAP1L1′s ability to mediate chromatin structure is essential for DNA replication and cell proliferation, making NAP1L1 a key player in maintaining genomic stability. Furthermore, NAP1L1 shares a 54% sequence similarity with the Saccharomyces cerevisiae Nap1 protein, suggesting evolutionary conservation of function. Notably, NAP1L1 has been implicated as a potential genetic marker for intestinal carcinomas, underscoring NAP1L1′s relevance in cancer research and therapeutic development.

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NAP1L1 Antibody (2609C3a) References:

1. Direct interaction between nucleosome assembly protein 1 and the papillomavirus E2 proteins involved in activation of transcription.  |  Rehtanz, M., et al. 2004. Mol Cell Biol. 24: 2153-68. PMID: 14966293
2. Assembly and disassembly of nucleosome core particles containing histone variants by human nucleosome assembly protein I.  |  Okuwaki, M., et al. 2005. Mol Cell Biol. 25: 10639-51. PMID: 16287874
3. The role of genetic markers--NAP1L1, MAGE-D2, and MTA1--in defining small-intestinal carcinoid neoplasia.  |  Kidd, M., et al. 2006. Ann Surg Oncol. 13: 253-62. PMID: 16424981
4. Genetic differentiation of appendiceal tumor malignancy: a guide for the perplexed.  |  Modlin, IM., et al. 2006. Ann Surg. 244: 52-60. PMID: 16794389
5. Identification of novel proteins induced by estradiol, 4-hydroxytamoxifen and acolbifene in T47D breast cancer cells.  |  Al-Dhaheri, MH., et al. 2006. Steroids. 71: 966-78. PMID: 16949628
6. The nucleosome assembly activity of NAP1 is enhanced by Alien.  |  Eckey, M., et al. 2007. Mol Cell Biol. 27: 3557-68. PMID: 17339334

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-NAP1L1 Antibody (2609C3a) has 2 citations in a variety of scientific publications.

Primary antibodies like Anti-NAP1L1 Antibody (2609C3a) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

NAP1L1 Antibody (2609C3a) Specifications

Alternate Product Name: NAP1L1

Product Clone Name: 2609C3a

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: NAP1L1

Epitope Species: human

Product Reactivity/Detection: NAP1L1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 1.0% stabilizer protein

Research Citations: 2 citations in various scientific publications

Available Conjugates/Forms for NAP1L1 Antibody (2609C3a): N/A