beta 1 Sodium Potassium ATPase/ATP1B1 Antibody (3C115): sc-71635

Na+/K+-ATPase β1 Antibody (3C115) is a mouse monoclonal IgG2a antibody that detects Na+/K+-ATPase β1 in mouse, rat, human, rabbit, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Na+/K+-ATPase β1 is a crucial component of the sodium/potassium-ATPase complex, which maintains cellular homeostasis by regulating ion gradients across the plasma membrane. Na+/K+-ATPase β1 is primarily located in the plasma membrane of various cell types, where Na+/K+-ATPase β1 plays a vital role in the proper functioning of the Na+/K+-ATPase pump. The β1 subunit is particularly important for the correct folding and insertion of the α subunit into the membrane, ensuring that the pump operates efficiently. Additionally, the β1 subunit is involved in the modulation of the pump′s activity and stability, which is critical for maintaining the resting membrane potential and facilitating Na+-coupled solute transport. The interaction of Na+/K+-ATPase β1 with the α subunit and glycosylation status influence the overall functionality of the enzyme complex, making Na+/K+-ATPase β1 a key player in cellular physiology and a valuable target for research in various physiological and pathological contexts.

The preferred beta 1 Sodium Potassium ATPase/ATP1B1 antibody is beta 1 Sodium Potassium ATPase/ATP1B1 Antibody (C464.8): sc-21713.