alpha 3 Sodium Potassium ATPase/ATP1A3 Antibody (F-1): sc-374050
- alpha 3 Sodium Potassium ATPase/ATP1A3 Antibody (F-1) is a mouse monoclonal IgG3 κ, cited in 6 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 419-446 within an internal region of Na+/K+-ATPase α3 of human origin
- recommended for detection of Na+/K+-ATPase α3 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and porcine
- See ATP1A1/ATP1A2/ATP1A3/ATP1A4 (M7-PB-E9): sc-58628 for alpha 3 Sodium Potassium ATPase/ATP1A3 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG3 BP-HRP is the preferred secondary detection reagent for alpha 3 Sodium Potassium ATPase/ATP1A3 Antibody (F-1) for WB applications. This reagent is now offered in a bundle with alpha 3 Sodium Potassium ATPase/ATP1A3 Antibody (F-1) (see ordering information below).
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SEE ALSO...
Na+/K+-ATPase α3 Antibody (F-1) is a mouse monoclonal IgG3 antibody that detects Na+/K+-ATPase α3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Na+/K+-ATPase α3 is a vital component of the sodium/potassium-ATPase complex, which is crucial for maintaining cellular homeostasis by regulating ion gradients across the plasma membrane. Na+/K+-ATPase α3 is primarily located in the plasma membrane of various cell types, where Na+/K+-ATPase α3 plays a significant role in controlling cellular volume and membrane potential. Proper functioning of Na+/K+-ATPase α3 is essential for numerous physiological processes, including muscle contraction, nerve impulse transmission, and nutrient absorption. Disruption of Na+/K+-ATPase α3 activity can lead to severe pathophysiological conditions, such as hypertension and heart failure. The Na+/K+-ATPase complex is composed of multiple isoforms of three subunits: α, β, and γ, with the α subunit being responsible for ATP binding and cation transport. The β subunit is critical for the correct folding and membrane insertion of the α subunit, while the γ subunit enhances the affinity of the complex for ATP in specific nephron segments. Na+/K+-ATPase α3 Antibody (F-1) is an invaluable tool for researchers studying the intricate mechanisms of ion transport and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
alpha 3 Sodium Potassium ATPase/ATP1A3 Antibody (F-1) | sc-374050 | 200 µg/ml | $322.00 | |||
alpha 3 Sodium Potassium ATPase/ATP1A3 Antibody (F-1): m-IgG3 BP-HRP Bundle | sc-550447 | 200 µg Ab; 40 µg BP | $361.00 | |||
alpha 3 Sodium Potassium ATPase/ATP1A3 (F-1) Neutralizing Peptide | sc-374050 P | 100 µg/0.5 ml | $69.00 |