Date published: 2026-5-4

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N8-Acetylspermidine dihydrochloride (CAS 34450-15-2)

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Application:
N8-Acetylspermidine dihydrochloride is A substrate for acetylspermidine deacetylase
CAS Number:
34450-15-2
Purity:
≥95%
Molecular Weight:
260.20
Molecular Formula:
C9H21N3O•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N8-Acetylspermidine dihydrochloride is a substrate for acetylspermidine deacetylase. It is utilized in the synthesis of biologically active compounds such as peptides and proteins. Although the exact mechanism of how it works is not fully understood, it is thought to function as an inhibitor of certain enzymes. Thus, the substance has been used in studies of enzyme kinetics and protein folding. Additionally, N8-Acetylspermidine dihydrochloride impacts the metabolism of various compounds, including glucose and fatty acids.


N,[object Object],-Acetylspermidine dihydrochloride (CAS 34450-15-2) References

  1. A mechanism of vasodilatory action of polyamines and acetylpolyamines: possible involvement of their Ca2+ antagonistic properties.  |  Myung, CS., et al. 2000. J Pharm Pharmacol. 52: 695-707. PMID: 10875547
  2. Barley polyamine oxidase: characterisation and analysis of the cofactor and the N-terminal amino acid sequence.  |  Radová, A., et al. 2001. Phytochem Anal. 12: 166-73. PMID: 11705021
  3. Spermidine nuclear acetylation in rat hepatocytes and in logarithmically growing rat hepatoma cells: comparison with histone acetylation.  |  Desiderio, MA., et al. 1992. Exp Cell Res. 202: 501-6. PMID: 1397102
  4. Simultaneous determination of different polyamines and their mono-acetylated derivatives in gastric tissue by HPLC with post-column derivatization.  |  Raza, M. and Al-Shabanah, OA. 2010. Sci Pharm. 78: 249-58. PMID: 21179346
  5. Increased bacterial putrescine has no impact on gut morphology and physiology in gnotobiotic adolescent mice.  |  Slezak, K., et al. 2013. Benef Microbes. 4: 253-66. PMID: 23666100
  6. Enriched metabolites that potentially promote age-associated diseases in subjects with an elderly-type gut microbiota.  |  Yoshimoto, S., et al. 2021. Gut Microbes. 13: 1-11. PMID: 33430687
  7. The effect of acylated polyamine derivatives on polyamine uptake mechanism, cell growth, and polyamine pools in Escherichia coli, and the pursuit of structure/activity relationships.  |  Karahalios, P., et al. 1998. Eur J Biochem. 251: 998-1004. PMID: 9490078

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N8-Acetylspermidine dihydrochloride, 50 mg

sc-236151A
50 mg
$385.00

N8-Acetylspermidine dihydrochloride, 100 mg

sc-236151
100 mg
$634.00

N8-Acetylspermidine dihydrochloride, 500 mg

sc-236151B
500 mg
$2393.00