N-Myc Antibody (NMYC-1): sc-80546
- N-Myc Antibody (NMYC-1) is a mouse monoclonal IgG2a, cited in 2 publications, provided at 200 µg/ml
- epitope mapping at residues 327-339 of N-Myc of human origin
- recommended for detection of N-Myc p67 of mouse, rat and human origin by WB, IP and IF
- See N-Myc (B8.4.B): sc-53993 for N-Myc antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for N-Myc Antibody (NMYC-1). This work is in progress.
N-Myc Antibody (NMYC-1) is a mouse monoclonal IgG2a antibody that detects N-Myc in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). N-Myc is a crucial member of the Myc family of oncogenes, which play a significant role in cell proliferation, differentiation, and apoptosis. N-Myc is primarily located in the nucleus, where N-Myc functions as a transcription factor regulating gene expression involved in cell growth and metabolism. This nuclear localization enables N-Myc to interact directly with DNA and other nuclear proteins, influencing cellular processes that can lead to tumorigenesis when dysregulated. Notably, aberrant expression of N-Myc is often associated with aggressive forms of cancer, such as neuroblastoma, where N-Myc amplification correlates with disease progression. Anti-N-Myc antibody (NMYC-1) provides a reliable tool for researchers studying N-Myc′s role in cancer biology and potential as a therapeutic target.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Myc Antibody (NMYC-1) | sc-80546 | 200 µg/ml | $322.00 |