N-Methylquipazine dimaleate (CAS 28614-26-8)
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N-Methylquipazine dimaleate is a chemical that functions as a potent and selective serotonin 5-HT3 receptor antagonist. It acts by binding to the 5-HT3 receptor and inhibiting the action of serotonin, a neurotransmitter involved in various physiological processes. N-Methylquipazine Dimaleate′s mechanism of action involves blocking the activation of the 5-HT3 receptor, which is a ligand-gated ion channel found in the central and peripheral nervous systems. By antagonizing this receptor, N-Methylquipazine dimaleate can modulate the release of neurotransmitters such as dopamine, norepinephrine, and acetylcholine, thereby affecting neuronal signaling and synaptic transmission. N-Methylquipazine Dimaleate′s function in experimental applications involves studying the role of the 5-HT3 receptor in various physiological and pathological conditions.
N-Methylquipazine dimaleate (CAS 28614-26-8) References
- Binding of arylpiperazines to 5-HT3 serotonin receptors: results of a structure-affinity study. | Glennon, RA., et al. 1989. Eur J Pharmacol. 168: 387-92. PMID: 2583244
- Serotonin limits generation of chromaffin cells during adrenal organ development. | Kameneva, P., et al. 2022. Nat Commun. 13: 2901. PMID: 35614045
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Methylquipazine dimaleate, 20 mg | sc-203639 | 20 mg | $93.00 | |||
N-Methylquipazine dimaleate, 100 mg | sc-203639A | 100 mg | $145.00 |