Myosin Ie Antibody (7A5): sc-293354

Myosin Ie Antibody (7A5) is a mouse monoclonal IgG2a kappa light chain antibody that detects Myosin Ie protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-Myosin Ie antibody (7A5) is available as non-conjugated format. Myosin Ie, also known as Myosin Ic, plays a critical role in cellular motility and is involved in various essential processes such as cytokinesis, phagocytosis, and muscle contraction. Myosin Ie is primarily located in the cytoplasm, where Myosin Ie interacts with actin filaments to facilitate movement and shape changes in cells. Proper localization of Myosin Ie is vital for maintaining cellular architecture and function, ensuring that contractile apparatus operates efficiently during dynamic cellular activities. Myosin Ie consists of 1,109 amino acids and forms a hexameric structure composed of two heavy chains and four light chains, which is essential for interaction with actin. Formation of stable complexes with actin by Myosin Ie is crucial for generating mechanical forces required for various cellular movements, making Myosin Ie an important target for research in cell biology and muscle physiology.

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Myosin Ie Antibody (7A5) References:

1. The kinetic mechanism of Myo1e (human myosin-IC).  |  El Mezgueldi, M., et al. 2002. J Biol Chem. 277: 21514-21. PMID: 11940582
2. Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia.  |  Dumont, RA., et al. 2002. J Assoc Res Otolaryngol. 3: 375-89. PMID: 12486594
3. Differential expression and molecular characterisation of Lmo7, Myo1e, Sash1, and Mcoln2 genes in Btk-defective B-cells.  |  Lindvall, JM., et al. 2005. Cell Immunol. 235: 46-55. PMID: 16137664
4. Chromosomal location of three unconventional myosin heavy chain genes in the mouse.  |  Whitmer, JD., et al. 1996. Genomics. 38: 235-7. PMID: 8954808

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Myosin Ie Antibody (7A5) has 2 citations in a variety of scientific publications.

Primary antibodies like Anti-Myosin Ie Antibody (7A5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Myosin Ie Antibody (7A5) Specifications

Alternate Product Name: Myosin Ie

Product Clone Name: 7A5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 918-1014

Epitope Target: Myosin Ie

Epitope Species: human

Product Reactivity/Detection: Myosin Ie

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 2 citations in various scientific publications

Available Conjugates/Forms for Myosin Ie Antibody (7A5): N/A