myoglobin Antibody (A-6): sc-393020
- myoglobin Antibody (A-6) is a mouse monoclonal IgG1 κ myoglobin antibody, cited in 8 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 123-151 at the C-terminus of myoglobin of mouse origin
- myoglobin Antibody (A-6) is recommended for detection of myoglobin of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-myoglobin Antibody (A-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for myoglobin Antibody (A-6) for WB applications. These reagents are now offered in bundles with myoglobin Antibody (A-6) (see ordering information below).
QUICK LINKS
SEE ALSO...
Myoglobin Antibody (A-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects myoglobin protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-myoglobin antibody (A-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Myoglobin is a crucial cytosolic oxygen-binding protein primarily located in skeletal and cardiac muscle, where myoglobin plays a vital role in oxygen storage and diffusion within myocytes. Myoglobin is essential for maintaining mitochondrial respiration during intense and prolonged muscle activity, facilitating oxygen transport from erythrocytes to mitochondria, which is critical for energy production in muscle cells. Myoglobin′s structure, characterized by a heme group, allows effective oxygen binding and release, making myoglobin indispensable for muscle function, especially during periods of high demand. The genomic structure of myoglobin is conserved across various species, featuring a putative polyadenylation signal and a polypyrimidine-rich region, with human myoglobin being specified by a single gene that has also been identified in human smooth muscle.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
myoglobin Antibody (A-6) References:
- Implication of CO inactivation on myoglobin function. | Chung, Y., et al. 2006. Am J Physiol Cell Physiol. 290: C1616-24. PMID: 16421206
- Redox properties of engineered ruthenium myoglobin. | Li, CZ., et al. 2009. Bioelectrochemistry. 75: 182-8. PMID: 19427819
- Quantitative nephelometric assay for determining myoglobin evaluated. | Delanghe, JR., et al. 1990. Clin Chem. 36: 1675-8. PMID: 2208710
- Human haptoglobin binds to human myoglobin. | Sakata, S., et al. 1986. Biochim Biophys Acta. 873: 312-5. PMID: 3756181
- Cryogenic stabilization of myoglobin photoproducts. | Sassaroli, M., et al. 1986. J Biol Chem. 261: 13704-13. PMID: 3759989
- Permeability of muscle capillaries to exogenous myoglobin. | Simionescu, N., et al. 1973. J Cell Biol. 57: 424-52. PMID: 4696549
- Serum myoglobin in thyroid disease. | Karlsson, FA., et al. 1980. Acta Endocrinol (Copenh). 94: 184-7. PMID: 6893384
- In vitro responses of myoglobin-primed lymph node cells to myoglobin and myoglobin synthetic antigenic peptides. | Stavitsky, AB., et al. 1978. Adv Exp Med Biol. 98: 199-219. PMID: 82384
- Mechanism of hydrogen cyanide binding to myoglobin. | Dou, Y., et al. 1996. Biochemistry. 35: 7107-13. PMID: 8679537
- Calibrated histochemistry of myoglobin concentration in cardiomyocytes. | Lee-de Groot, MB., et al. 1998. J Histochem Cytochem. 46: 1077-84. PMID: 9705974
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
myoglobin Antibody (A-6) | sc-393020 | 200 µg/ml | $316.00 | |||
myoglobin Antibody (A-6): m-IgG Fc BP-HRP Bundle | sc-527663 | 200 µg Ab; 10 µg BP | $354.00 | |||
myoglobin Antibody (A-6): m-IgG1 BP-HRP Bundle | sc-533036 | 200 µg Ab; 20 µg BP | $354.00 | |||
myoglobin Antibody (A-6) AC | sc-393020 AC | 500 µg/ml, 25% agarose | $416.00 | |||
myoglobin Antibody (A-6) HRP | sc-393020 HRP | 200 µg/ml | $316.00 | |||
myoglobin Antibody (A-6) FITC | sc-393020 FITC | 200 µg/ml | $330.00 | |||
myoglobin Antibody (A-6) PE | sc-393020 PE | 200 µg/ml | $343.00 | |||
myoglobin Antibody (A-6) Alexa Fluor® 488 | sc-393020 AF488 | 200 µg/ml | $357.00 | |||
myoglobin Antibody (A-6) Alexa Fluor® 546 | sc-393020 AF546 | 200 µg/ml | $357.00 | |||
myoglobin Antibody (A-6) Alexa Fluor® 594 | sc-393020 AF594 | 200 µg/ml | $357.00 | |||
myoglobin Antibody (A-6) Alexa Fluor® 647 | sc-393020 AF647 | 200 µg/ml | $357.00 | |||
myoglobin Antibody (A-6) Alexa Fluor® 680 | sc-393020 AF680 | 200 µg/ml | $357.00 | |||
myoglobin Antibody (A-6) Alexa Fluor® 790 | sc-393020 AF790 | 200 µg/ml | $357.00 | |||
myoglobin (A-6) Neutralizing Peptide | sc-393020 P | 100 µg/0.5 ml | $68.00 |