myogenin Antibody (D-10): sc-13137
- myogenin Antibody (D-10) is a mouse monoclonal IgG3 κ, cited in 16 publications, provided at 200 µg/ml
- raised against amino acids 1-225 of myogenin of human origin
- recommended for detection of myogenin of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for Gel Supershift and ChIP applications (sc-13137 X, 200 µg/0.1 ml)
- See myogenin (5FD): sc-52903 for myogenin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for myogenin Antibody (D-10). This work is in progress.
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myogenin Antibody (D-10) is a mouse monoclonal IgG3 kappa light chain antibody raised against amino acids 1-225 of human myogenin, a muscle-specific transcription factor also known as MYOG. myogenin monoclonal antibody (D-10) is validated for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA), and reacts with proteins from mouse, rat, and human species. myogenin belongs to the myogenic regulatory factor (MRF) family, which includes MyoD, Myf-5, and Myf-6 (MRF4 or herculin), all of which are key regulators of muscle cell differentiation. myogenin functions as a basic helix-loop-helix (bHLH) transcription factor that forms heterodimers with E proteins, such as E2A and HEB, enabling binding to E-box sequences (CANNTG) in the promoter regions of muscle-specific genes. Expression is activated during the transition from myoblasts to differentiated muscle cells, making myogenin essential for the development of functional skeletal muscle. By controlling the transcription of genes involved in terminal differentiation, myogenin ensures the proper formation and repair of muscle tissue. Aberrations in myogenin expression can impact muscle development and regeneration, highlighting myogenin′s critical role in myogenesis. myogenin monoclonal antibody (D-10) is a valuable resource for studying the mechanisms of muscle differentiation and development.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
myogenin Antibody (D-10) | sc-13137 | 200 µg/ml | $316.00 | |||
myogenin Antibody (D-10) X | sc-13137 X | 200 µg/0.1 ml | $316.00 |