MyoD Antibody (4H207): sc-71629
- MyoD Antibody (4H207) is a mouse monoclonal IgG1 κ, cited in 19 publications, provided at 200 µg/ml
- raised against recombinant MyoD of mouse origin with an epitope mapping to amino acids 180-189
- recommended for detection of MyoD of mouse, rat and human origin by WB, IP, IF and IHC(P); non cross-reactive with other MyoD family members
- See MyoD (G-1): sc-377460 for MyoD antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG1 BP-HRP is the preferred secondary detection reagent for MyoD Antibody (4H207) for WB and IHC(P) applications. This reagent is now offered in a bundle with MyoD Antibody (4H207) (see ordering information below).
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MyoD Antibody (4H207) is a mouse monoclonal IgG1 kappa light chain antibody engineered to detect Myogenic Differentiation 1 (MyoD), also known as MRF1, a key member of the Myogenic Regulatory Factors (MRFs) family that includes myogenin, Myf5, and MRF4 (herculin). Anti-MyoD antibody (4H207) is raised against recombinant mouse MyoD, targeting an epitope within amino acids 180-189 to ensure precise binding. MyoD is predominantly located in the nucleus of muscle cells, where MyoD functions as a transcription factor by binding to E-box sequences (CANNTG) in DNA to regulate the expression of genes essential for muscle differentiation and development. By forming heterodimers with E proteins such as E2A, IF2, and HEB, MyoD activates the transcription of muscle-specific genes, playing a vital role in myogenesis and muscle regeneration. The nuclear localization of MyoD is crucial for controlling gene expression and orchestrating the differentiation process. MyoD monoclonal antibody (4H207) is validated for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry applications across multiple species, including mouse, rat, and human, without cross-reacting with other members of the MyoD family. Available in both conjugated and non-conjugated forms, MyoD (4H207) antibody offers flexibility for various experimental setups. Anti-MyoD antibody (4H207) is recommended for researchers investigating the molecular mechanisms underlying muscle cell differentiation and regeneration.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MyoD Antibody (4H207) | sc-71629 | 200 µg/ml | $316.00 | |||
MyoD Antibody (4H207): m-IgG1 BP-HRP Bundle | sc-542616 | 200 µg Ab; 20 µg BP | $354.00 |