Myeloid lineage Antibody (OX82): sc-53093
- Myeloid lineage Antibody (OX82) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specifically recognizes a 35 kDa molecule on myeloid cells and stromal elements from a variety of tissues of adult rat origin
- Anti-Myeloid lineage Antibody (OX82) is recommended for detection of Myeloid lineage of mouse and rat origin by WB, IP and FCM
- Anti-Myeloid lineage Antibody (OX82) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Myeloid lineage Antibody (OX82) for WB applications. These reagents are now offered in bundles with Myeloid lineage Antibody (OX82) (see ordering information below).
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Myeloid lineage Antibody (OX82) is a mouse monoclonal IgG1 kappa light chain antibody that detects Myeloid lineage of mouse and rat origin by western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). Myeloid lineage (OX82) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Myeloid lineage plays a crucial role in the immune response, encompassing a variety of cell types, including monocytes, macrophages, neutrophils, and dendritic cells, all essential for pathogen recognition and clearance. These cells originate from hematopoietic stem cells in the bone marrow and mediate inflammation while orchestrating the body′s defense mechanisms. The differentiation of Myeloid lineage cells is tightly regulated by transcription factors such as BLIMP-1, ensuring proper development of these immune cells. Understanding Myeloid lineage is vital for diagnosing and treating various hematological malignancies, as well as for developing targeted therapies that can modulate immune responses in diseases such as cancer and autoimmune disorders. Myeloid lineage cells produce inflammatory cytokines upon activation, highlighting their importance in both innate and adaptive immunity.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Myeloid lineage Antibody (OX82) References:
- BLIMP-1: trigger for differentiation of myeloid lineage. | Chang, DH., et al. 2000. Nat Immunol. 1: 169-76. PMID: 11248811
- Kaposi's sarcoma-associated herpesvirus OX2 glycoprotein activates myeloid-lineage cells to induce inflammatory cytokine production. | Chung, YH., et al. 2002. J Virol. 76: 4688-98. PMID: 11967286
- HIF-1alpha is essential for myeloid cell-mediated inflammation. | Cramer, T., et al. 2003. Cell. 112: 645-57. PMID: 12628185
- Determinants of lymphoid-myeloid lineage diversification. | Laiosa, CV., et al. 2006. Annu Rev Immunol. 24: 705-38. PMID: 16551264
- Cell death in the myeloid lineage. | Cotter, TG., et al. 1994. Immunol Rev. 142: 93-112. PMID: 7698803
- Molecular diagnostic testing for determination of myeloid lineage in acute leukemias. | Crisan, D. 1994. Ann Clin Lab Sci. 24: 355-63. PMID: 7944272
- Detection of mouse IL-8 receptor homologue expression on peripheral blood leukocytes and mature myeloid lineage cells in bone marrow. | Wang, J., et al. 1996. J Leukoc Biol. 60: 372-81. PMID: 8830794
- In vitro differentiation of murine Sca-1+Lin- cells into myeloid, B cell and T cell lineages. | Ito, M., et al. 1996. Stem Cells. 14: 412-8. PMID: 8843542
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Myeloid lineage Antibody (OX82) | sc-53093 | 200 µg/ml | $316.00 | |||
Myeloid lineage Antibody (OX82): m-IgG Fc BP-HRP Bundle | sc-526767 | 200 µg Ab; 10 µg BP | $354.00 | |||
Myeloid lineage Antibody (OX82): m-IgG1 BP-HRP Bundle | sc-532140 | 200 µg Ab; 20 µg BP | $354.00 | |||
Myeloid lineage Antibody (OX82) AC | sc-53093 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Myeloid lineage Antibody (OX82) HRP | sc-53093 HRP | 200 µg/ml | $316.00 | |||
Myeloid lineage Antibody (OX82) FITC | sc-53093 FITC | 200 µg/ml | $330.00 | |||
Myeloid lineage Antibody (OX82) PE | sc-53093 PE | 200 µg/ml | $343.00 | |||
Myeloid lineage Antibody (OX82) Alexa Fluor® 488 | sc-53093 AF488 | 200 µg/ml | $357.00 | |||
Myeloid lineage Antibody (OX82) Alexa Fluor® 546 | sc-53093 AF546 | 200 µg/ml | $357.00 | |||
Myeloid lineage Antibody (OX82) Alexa Fluor® 594 | sc-53093 AF594 | 200 µg/ml | $357.00 | |||
Myeloid lineage Antibody (OX82) Alexa Fluor® 647 | sc-53093 AF647 | 200 µg/ml | $357.00 | |||
Myeloid lineage Antibody (OX82) Alexa Fluor® 680 | sc-53093 AF680 | 200 µg/ml | $357.00 | |||
Myeloid lineage Antibody (OX82) Alexa Fluor® 790 | sc-53093 AF790 | 200 µg/ml | $357.00 |