Mycobacterium tuberculosis RV3134 Dormancy Regulon Antibody (B10) is a mouse monoclonal IgG3 antibody that detects RV3134 in Mycobacterium tuberculosis by western blotting (WB). Mycobacterium tuberculosis, the leading cause of tuberculosis, is a Gram-positive obligate anaerobe that can remain dormant within the human host for extended periods, evading the immune response and complicating treatment. RV3134 is a crucial component of the M. tuberculosis dormancy regulon, playing a significant role in the bacterium′s ability to adapt to hostile environments, particularly during periods of low oxygen tension. RV3134 expression is upregulated in response to environmental stressors, which is vital for the pathogen′s survival and persistence in the host. Understanding RV3134 function not only sheds light on the mechanisms of dormancy in M. tuberculosis but also highlights potential targets for therapeutic intervention, as disrupting RV3134 function could render the bacteria more susceptible to treatment. Anti-RV3134 antibody (B10) is an essential tool for researchers studying the dormancy and pathogenicity of this critical human pathogen.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Mycobacterium tuberculosis RV3134 Dormancy Regulon Antibody (B10) References:
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