Multimerin-2 Antibody (6D365): sc-71624

Multimerin-2 Antibody (6D365) is a mouse monoclonal IgG antibody that detects Multimerin-2 in human samples through immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Multimerin-2, also known as Emilin-3 or EndoGlyx-1, plays a crucial role in the extracellular matrix, particularly in elastin-rich tissues like blood vessels, skin, heart, and lung, where Multimerin-2 contributes to structural integrity and elasticity. Multimerin-2 is characterized by an EMI domain, which is essential for interaction with elastin and microfibrils, thereby influencing tissue resilience and repair. Multimerin-2 is expressed during embryonic development and is particularly prominent at sites of cartilage and bone formation, highlighting Multimerin-2′s importance in skeletal development. Multimerin-2 is more readily detected in immature osteoblasts compared to mature osteoblasts, suggesting a role in early bone formation processes. Multimerin-2′s presence in the nervous plexus of the digestive tract and main bronchial branches during later developmental stages underscores Multimerin-2′s diverse functional significance in various biological contexts. Anti-Multimerin-2 antibody (6D365) serves as an invaluable tool for researchers investigating the dynamics of extracellular matrix proteins and their implications in developmental biology and tissue engineering.

The preferred Multimerin-2 antibody is Multimerin-2 Antibody (H572): sc-65432.