Multimerin-2 Antibody (H572): sc-65432

Multimerin-2 Antibody (H572) is a mouse monoclonal IgG antibody that detects Multimerin-2 protein of human origin by immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Anti-Multimerin-2 antibody (H572) is available as a non-conjugated format. Multimerin-2, also known as Emilin-3 or EndoGlyx-1, plays a crucial role in the extracellular matrix, particularly in elastin-rich tissues such as blood vessels, skin, heart, and lung. Multimerin-2 belongs to the EMILIN family of proteins, characterized by the presence of an EMI domain, which is essential for maintaining the structural integrity of the extracellular matrix. Multimerin-2 is involved in the regulation of cell adhesion and migration, processes vital for tissue development and repair. During embryonic development, Multimerin-2 is expressed at critical sites of cartilage and bone formation, highlighting its importance in skeletal development. Multimerin-2 expression in the nervous plexus of the digestive tract and main bronchial branches during later stages of development underscores diverse roles in various physiological contexts. Multimerin-2′s interaction with other proteins in the extracellular matrix enhances functional significance, making anti-Multimerin-2 antibody (H572) a valuable tool for researchers studying developmental biology and tissue engineering.

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Multimerin-2 Antibody (H572) References:

1. EMILIN, a component of the elastic fiber and a new member of the C1q/tumor necrosis factor superfamily of proteins.  |  Doliana, R., et al. 1999. J Biol Chem. 274: 16773-81. PMID: 10358019
2. Structure, chromosomal localization, and promoter analysis of the human elastin microfibril interfase located proteIN (EMILIN) gene.  |  Doliana, R., et al. 2000. J Biol Chem. 275: 785-92. PMID: 10625608
3. The EMILIN protein family.  |  Colombatti, A., et al. 2000. Matrix Biol. 19: 289-301. PMID: 10963989
4. EMI, a novel cysteine-rich domain of EMILINs and other extracellular proteins, interacts with the gC1q domains and participates in multimerization.  |  Doliana, R., et al. 2000. FEBS Lett. 484: 164-8. PMID: 11068053
5. Molecular cloning and characterization of EndoGlyx-1, an EMILIN-like multisubunit glycoprotein of vascular endothelium.  |  Christian, S., et al. 2001. J Biol Chem. 276: 48588-95. PMID: 11559704
6. Developmental expression and biochemical characterization of Emu family members.  |  Leimeister, C., et al. 2002. Dev Biol. 249: 204-18. PMID: 12221002
7. Molecular cloning and characterization of a novel gene, EMILIN-5, and its possible involvement in skeletal development.  |  Doi, M., et al. 2004. Biochem Biophys Res Commun. 313: 888-93. PMID: 14706625
8. Multimerin: a bench-to-bedside chronology of a unique platelet and endothelial cell protein--from discovery to function to abnormalities in disease.  |  Hayward, CP. 1997. Clin Invest Med. 20: 176-87. PMID: 9189649
9. Multimerin.  |  Hayward, CP. and Kelton, JG. 1995. Curr Opin Hematol. 2: 339-44. PMID: 9372017

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Multimerin-2 Antibody (H572) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Multimerin-2 Antibody (H572) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Multimerin-2 Antibody (H572) Specifications

Alternate Product Name: Multimerin-2

Product Clone Name: H572

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Multimerin-2

Epitope Species: human

Product Reactivity/Detection: Multimerin-2

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IP, IF, FCM

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Multimerin-2 Antibody (H572): N/A