Mucin 1/MUC1 Antibody (E29): sc-53377
- Mucin 1/MUC1 Antibody (E29) is a mouse monoclonal IgG2a λ, cited in 5 publications, provided at 200 µg/ml
- raised against milk fat globule membrane preparation of human origin
- recommended for detection of Mucin 1 of human origin by WB, IP, IF and IHC(P)
- also available conjugated to Alexa Fluor® 488 for IF, IHC(P) and FCM
- See Mucin 1/MUC1 (VU4H5): sc-7313 for Mucin 1/MUC1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP) is the preferred secondary detection reagent for Mucin 1/MUC1 Antibody (E29) for WB and IHC(P) applications. This reagent is now offered in a bundle with Mucin 1/MUC1 Antibody (E29) (see ordering information below). For additional m-IgGλ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Mucin 1 Antibody (E29) is a mouse monoclonal IgG2a antibody that detects Mucin 1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Mucin 1 plays a crucial role in cell signaling and adhesion, acting as a protective barrier on epithelial surfaces and contributing to the maintenance of tissue integrity. Mucin 1′s aberrant expression is particularly significant in epithelial tumors, such as breast carcinomas, where Mucin 1 can influence tumor progression and metastasis. Mucin 1 is primarily localized to the apical surface of epithelial cells, where Mucin 1 forms a gel-like layer that traps pathogens and particulates, thereby playing a vital role in the immune response. Mucin 1′s structure, characterized by a large extracellular domain rich in glycosylation, not only enhances protective functions but also modulates interactions with other proteins, including those involved in cell signaling pathways. Anti-Mucin 1 antibody (E29) is an essential tool for researchers investigating the role of mucins in cancer biology and epithelial cell function, providing insights into potential therapeutic targets and biomarkers for disease progression.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mucin 1/MUC1 Antibody (E29) | sc-53377 | 200 µg/ml | $322.00 | |||
Mucin 1/MUC1 Antibody (E29): m-IgGλ BP-HRP Bundle | sc-520973 | 200 µg Ab, 40 µg BP | $361.00 | |||
Mucin 1/MUC1 Antibody (E29) Alexa Fluor® 488 | sc-53377 AF488 | 200 µg/ml | $338.00 |