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MTSS1 Antibody (SS-3) is a mouse monoclonal IgG1 antibody that detects MTSS1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). MTSS1, also known as metastasis suppressor 1, MIM, MIMA, or MIMB, is a 755 amino acid protein characterized by one Actin-binding WH2 (Wiskott-Aldrich syndrome protein homology-2) domain and one IMD domain, which are crucial for function. MTSS1 is predominantly expressed in tissues such as testis, thymus, prostate, spleen, colon, uterus, and blood, where MTSS1 plays a significant role in binding to Actin and influencing cytoskeleton dynamics. MTSS1 acts as a tumor suppressor by regulating progression and metastasis of carcinomas across various organ sites. When MTSS1 is overexpressed, abnormal actin structures can form, potentially resulting in tumorigenesis. MTSS1 exists in three isoforms due to alternative splicing, which may contribute to diverse functional roles in cellular processes. MTSS1 (SS-3) antibody is an essential tool for researchers investigating mechanisms of cancer progression and cytoskeletal dynamics influenced by MTSS1.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MTSS1 Antibody (SS-3) | sc-101204 | 50 µg/0.5 ml | $333.00 |