MTHFS Antibody (YZ-M): sc-100563
- MTHFS Antibody (YZ-M) is a mouse monoclonal IgG1 κ provided at 100 µg/ml
- raised against recombinant MTHFS of human origin
- recommended for detection of MTHFS of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MTHFS Antibody (YZ-M). This work is in progress.
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SEE ALSO...
MTHFS Antibody (YZ-M) is a mouse monoclonal IgG1 antibody that detects MTHFS in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). MTHFS, or 5-formyltetrahydrofolate cyclo-ligase, is a crucial cytosolic protein that plays a significant role in the formate metabolic process, accounting for up to thirty percent of a cell′s cytoplasmic folate derivatives. MTHFS operates with a magnesium cofactor and catalyzes the ATP-dependent conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a vital step in the folate cycle. Folate is essential for DNA replication, and a deficiency in this molecule can lead to various disease states, including anemia and neural tube defects. During DNA replication, 5,10-methenyltetrahydrofolate is oxidized, and MTHFS is responsible for resetting this molecule, thereby ensuring the continuity of the folate cycle and proper synthesis of nucleic acids. Anti-MTHFS antibody (YZ-M) serves as an invaluable tool for researchers studying folate metabolism and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MTHFS Antibody (YZ-M) | sc-100563 | 100 µg/ml | $339.00 |