Date published: 2025-11-21

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MSANTD2 Antibody (B-8): sc-390361

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Datasheets
  • MSANTD2 Antibody (B-8) is a mouse monoclonal IgM κ MSANTD2 antibody provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 237-271 within an internal region of MSANTD2 of human origin
  • recommended for detection of MSANTD2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine and porcine; non cross-reactive with other C11orf family members
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MSANTD2 Antibody (B-8). This work is in progress.

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    MSANTD2 Antibody (B-8) is a mouse monoclonal IgM kappa antibody that detects MSANTD2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-MSANTD2 antibody (B-8) is available as the non-conjugated form. MSANTD2 plays a crucial role in regulating gene expression and is involved in various cellular processes, including cell differentiation and proliferation. MSANTD2 function is essential for maintaining cellular homeostasis and responding to environmental signals, which is particularly important in development and disease. Dysregulation of MSANTD2 has been implicated in several pathologies, including cancer, where altered expression levels can lead to uncontrolled cell growth. Understanding MSANTD2 function and interactions within the cellular environment can provide valuable insights into therapeutic targets and strategies for treating diseases associated with MSANTD2 dysfunction.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    MSANTD2 Antibody (B-8) References:

    1. The 11q terminal deletion disorder: a prospective study of 110 cases.  |  Grossfeld, PD., et al. 2004. Am J Med Genet A. 129A: 51-61. PMID: 15266616
    2. Human chromosome 11 DNA sequence and analysis including novel gene identification.  |  Taylor, TD., et al. 2006. Nature. 440: 497-500. PMID: 16554811
    3. KCNQ1 K+ channel-mediated cardiac channelopathies.  |  Loussouarn, G., et al. 2006. Methods Mol Biol. 337: 167-83. PMID: 16929947
    4. Skipping of Exon 1 in the KCNQ1 gene causes Jervell and Lange-Nielsen syndrome.  |  Zehelein, J., et al. 2006. J Biol Chem. 281: 35397-403. PMID: 16987820
    5. Beta-thalassaemia and sickle cell anaemia as paradigms of hypercoagulability.  |  Ataga, KI., et al. 2007. Br J Haematol. 139: 3-13. PMID: 17854302
    6. The subcellular localization of the Niemann-Pick Type C proteins depends on the adaptor complex AP-3.  |  Berger, AC., et al. 2007. J Cell Sci. 120: 3640-52. PMID: 17895371
    7. Wilms tumour: prognostic factors, staging, therapy and late effects.  |  Kaste, SC., et al. 2008. Pediatr Radiol. 38: 2-17. PMID: 18026723
    8. Activation and regulation of ATM kinase activity in response to DNA double-strand breaks.  |  Lee, JH. and Paull, TT. 2007. Oncogene. 26: 7741-8. PMID: 18066086
    9. Targeted cancer therapies based on the inhibition of DNA strand break repair.  |  O'Connor, MJ., et al. 2007. Oncogene. 26: 7816-24. PMID: 18066095
    10. Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder.  |  Lim, ET., et al. 2017. Nat Neurosci. 20: 1217-1224. PMID: 28714951
    11. The neurodevelopmental gene MSANTD2 belongs to a gene family formed by recurrent molecular domestication of Harbinger transposons at the base of vertebrates.  |  Etchegaray, E., et al. 2022. Mol Biol Evol. 39: PMID: 35980103
    12. LncRNA BCLET variant confers bladder cancer susceptibility through alternative splicing of MSANTD2 exon 1.  |  Liu, H., et al. 2023. Cancer Med. 12: 14440-14451. PMID: 37211917

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    MSANTD2 Antibody (B-8)

    sc-390361
    200 µg/ml
    $316.00

    MSANTD2 (B-8) Neutralizing Peptide

    sc-390361 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-390361 P appropriate for?

    Asked by: Dr Ninau Qelp
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Produced superb immunofluorescence cytoplasmicProduced superb immunofluorescence cytoplasmic and membrane staining in methanol-fixed HeLa cells. -SCBT QC
    Date published: 2015-05-04
    Rated 5 out of 5 by from Great Western Blot data of C11orf61 expressionGreat Western Blot data of C11orf61 expression in non-transfected 293T, human C11orf61 transfected 293T, PC-3, MCF7 and Ramos whole cell lysates. -SCBT QC
    Date published: 2014-09-01
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    MSANTD2 Antibody (B-8) is rated 5.0 out of 5 by 2.
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