MRP-L49 Antibody (H-12): sc-515183

MRP-L49 Antibody (H-12) is a mouse monoclonal IgG2a antibody that detects MRP-L49 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MRP-L49, also known as Neighbor of FAU and Protein NOF1, is a crucial mitochondrial ribosomal protein composed of 166 amino acids, which plays a vital role in the assembly of the 39S ribosomal subunit within mitochondria. MRP-L49 is essential for mitochondrial protein synthesis, a process critical for maintaining cellular energy production and overall cellular function. The gene encoding MRP-L49 is located on human chromosome 11, a region significant not only for high gene density, containing over 1,400 genes, but also for association with various genetic disorders, including Jervell and Lange-Nielsen syndrome and Jacobsen syndrome. Proper functioning of MRP-L49 is therefore important for mitochondrial health and preventing diseases linked to chromosomal abnormalities. Anti-MRP-L49 antibody (H-12) provides a reliable tool for researchers investigating mitochondrial function and related pathologies, enabling deeper insights into molecular mechanisms underlying these critical processes.

The preferred MRP-L49 antibody is MRP-L49 Antibody (G-11): sc-515160.