MRCKβ Antibody (D-7): sc-390076
- MRCKβ Antibody (D-7) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1637-1675 near the C-terminus of MRCKβ of human origin
- recommended for detection of MRCKβ of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgGκ BP-HRP is the preferred secondary detection reagent for MRCKβ Antibody (D-7) for WB applications. This reagent is now offered in a bundle with MRCKβ Antibody (D-7) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
MRCKβ Antibody (D-7) is a mouse monoclonal IgG3 antibody that detects MRCKβ in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MRCKβ, a member of the myotonic dystrophy kinase-related Cdc42-binding kinases family, plays a crucial role in regulating actin dynamics and cellular motility by phosphorylating nonmuscle myosin light chains, which in turn influences actin-myosin contractility. MRCKβ is primarily located in the cytoplasm, where MRCKβ interacts with various signaling pathways that are essential for processes such as cell migration and neurite outgrowth. The presence of a cysteine-rich motif and a pleckstrin homology domain in MRCKβ is significant as these structural features facilitate interaction with phospholipids and other proteins, thereby modulating activity in response to cellular signals. By understanding the function and localization of MRCKβ, researchers can gain insights into MRCKβ′s role in cellular processes and potential implications in diseases characterized by altered cell motility and cytoskeletal dynamics. Anti-MRCKβ antibody (D-7) is an invaluable tool for studying these mechanisms in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MRCKβ Antibody (D-7) | sc-390076 | 200 µg/ml | $322.00 | |||
MRCKβ Antibody (D-7): m-IgGκ BP-HRP Bundle | sc-523395 | 200 µg Ab, 40 µg BP | $361.00 | |||
MRCKβ (D-7) Neutralizing Peptide | sc-390076 P | 100 µg/0.5 ml | $69.00 |