MPP2 Antibody (D-9): sc-376913
- MPP2 Antibody (D-9) is a mouse monoclonal IgG2b MPP2 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 311-345 within an internal region of MPP2 of human origin
- MPP2 Antibody (D-9) is recommended for detection of MPP2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-MPP2 Antibody (D-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP is the preferred secondary detection reagent for MPP2 Antibody (D-9) for WB and IHC(P) applications. This reagent is now offered in a bundle with MPP2 Antibody (D-9) (see ordering information below).
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MPP2 (D-9) is a mouse monoclonal IgG2b antibody that detects MPP2 protein of mouse, rat and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP) and enzyme-linked immunosorbent assay (ELISA). MPP2 (clone D-9) antibody is available as both non-conjugated anti-MPP2 antibody form, as well as multiple conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC) and multiple Alexa Fluor® conjugates. The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression and signaling. The MAGUK family is divided into four subfamilies: DLG-like, ZO1-like, p55-like and LIN2-like. MPP2 (membrane protein, palmitoylated 2), also known as MAGUK p55 subfamily member 2, discs large homolog 2 or DLG2, is a 576 amino acid protein belonging to the MAGUK family that exists as three alternatively spliced isoforms. MPP2 contains one guanylate kinase-like domain, a PDZ (DHR) domain, two L27 domains and a single SH3 domain. The gene encoding MPP2 maps to the same segment of human chromosome 17 as MPP3, with whom MPP2 likely shares similar function and common structural organization.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MPP2 Antibody (D-9) References:
- Identification and characterization of human MPP7 gene and mouse Mpp7 gene in silico. | Katoh, M. and Katoh, M. 2004. Int J Mol Med. 13: 333-8. PMID: 14719143
- [MAGUKs: beyond ionic channel anchoring]. | Godreau, D., et al. 2004. Med Sci (Paris). 20: 84-8. PMID: 14770369
- The PDZ protein MPP2 interacts with c-Src in epithelial cells. | Baumgartner, M., et al. 2009. Exp Cell Res. 315: 2888-98. PMID: 19665017
- A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dIg-A. | Mazoyer, S., et al. 1995. Genomics. 28: 25-31. PMID: 7590743
- Isolation of a gene (DLG3) encoding a second member of the discs-large family on chromosome 17q12-q21. | Smith, SA., et al. 1996. Genomics. 31: 145-50. PMID: 8824795
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MPP2 Antibody (D-9) | sc-376913 | 200 µg/ml | $322.00 | |||
MPP2 Antibody (D-9): m-IgG2b BP-HRP Bundle | sc-548759 | 200 µg Ab; 10 µg BP | $361.00 | |||
MPP2 Antibody (D-9) AC | sc-376913 AC | 500 µg/ml, 25% agarose | $424.00 | |||
MPP2 Antibody (D-9) HRP | sc-376913 HRP | 200 µg/ml | $322.00 | |||
MPP2 Antibody (D-9) FITC | sc-376913 FITC | 200 µg/ml | $336.00 | |||
MPP2 Antibody (D-9) PE | sc-376913 PE | 200 µg/ml | $349.00 | |||
MPP2 Antibody (D-9) Alexa Fluor® 488 | sc-376913 AF488 | 200 µg/ml | $364.00 | |||
MPP2 Antibody (D-9) Alexa Fluor® 546 | sc-376913 AF546 | 200 µg/ml | $364.00 | |||
MPP2 Antibody (D-9) Alexa Fluor® 594 | sc-376913 AF594 | 200 µg/ml | $364.00 | |||
MPP2 Antibody (D-9) Alexa Fluor® 647 | sc-376913 AF647 | 200 µg/ml | $364.00 | |||
MPP2 Antibody (D-9) Alexa Fluor® 680 | sc-376913 AF680 | 200 µg/ml | $364.00 | |||
MPP2 Antibody (D-9) Alexa Fluor® 790 | sc-376913 AF790 | 200 µg/ml | $364.00 | |||
MPP2 (D-9) Neutralizing Peptide | sc-376913 P | 100 µg/0.5 ml | $69.00 |