MPO/Myeloperoxidase Antibody (266.6k2): sc-51741

MPO Antibody (266.6k2) is a mouse monoclonal IgG1 antibody that detects myeloperoxidase (MPO) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Anti-MPO antibody (266.6k2) plays a crucial role in understanding the function of MPO, which is essential for the immune response as MPO catalyzes the production of hypochlorous acid and other reactive oxygen species that are vital for microbial killing by neutrophils. MPO (266.6k2) monoclonal antibody enables research into proper MPO functioning, which is critical for optimal oxygen-dependent microbiocidal activity, making MPO a key player in the innate immune system. MPO primarily localizes in the azurophilic granules of neutrophils and is synthesized during the promyelocytic stage of myeloid differentiation, where MPO undergoes a series of post-translational modifications, including cotranslational N-linked glycosylation, which is important for proper folding and function. The glycosylation process not only aids in MPO maturation but also influences stability and interaction with other proteins, such as calreticulin, which assists in the proper folding of glycosylated MPO in the endoplasmic reticulum. MPO (266.6k2) antibody proves particularly valuable for researchers studying neutrophil biology and the mechanisms of immune response, as MPO (266.6k2) monoclonal antibody allows for detection and analysis of MPO in various experimental contexts.

The preferred MPO/Myeloperoxidase antibody is MPO/Myeloperoxidase Antibody (266-6K1): sc-52707.