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MOX-2 Antibody (F-7) is a mouse monoclonal IgM antibody that detects MOX-2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MOX-2, also known as mesenchyme homeobox 2 or GAX, plays a pivotal role in axial skeleton development, making MOX-2 essential for normal appendicular muscle formation and the regulation of myogenic genes. While MOX-2 is not required for the migration of myogenic precursors into the limb bud, MOX-2 expression is critical for the differentiation of these cells into functional muscle tissue. MOX-2 is predominantly expressed in placental tissue and is involved in the early steps of mesoderm formation during gastrulation, highlighting MOX-2′s importance in embryonic development. The human MEOX2 gene, which encodes MOX-2, is located on chromosome 7p21.1, and mutations in this gene have been linked to craniofacial and skeletal abnormalities, underscoring MOX-2′s significance in both developmental biology and potential clinical implications. Anti-MOX-2 antibody (F-7) is a valuable tool for researchers studying the intricate processes of muscle development and the underlying genetic factors that may contribute to developmental disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MOX-2 Antibody (F-7) | sc-390075 | 200 µg/ml | $316.00 | |||
MOX-2 (F-7) Neutralizing Peptide | sc-390075 P | 100 µg/0.5 ml | $68.00 |