MOX-1 Antibody (B-5): sc-398845
- MOX-1 Antibody (B-5) is a mouse monoclonal IgG2a κ MOX-1 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 67-81 within an internal region of MOX-1 of mouse origin
- MOX-1 Antibody (B-5) is recommended for detection of MOX-1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-MOX-1 Antibody (B-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-398845 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for MOX-1 Antibody (B-5) for WB applications. These reagents are now offered in bundles with MOX-1 Antibody (B-5) (see ordering information below).
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MOX-1 Antibody (B-5) is a mouse monoclonal IgG2a kappa light chain antibody that detects MOX-1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MOX-1 (B-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MOX-1, also known as Mesenchyme homeobox 1, plays a crucial role in the early stages of mesoderm formation during gastrulation, which is vital for proper embryonic development. MOX-1 is involved in the differentiation of mesodermal and mesenchymal derivatives, contributing to the formation of the axial skeleton. MOX-1 expression is first detected in the newly formed mesoderm of primitive streak stage mouse embryos, highlighting its importance in early developmental processes. MOX-1 interacts more strongly with Pax-1, a transcription factor essential for skeletal development, while MOX-2 preferentially associates with Pax-3. MEOX1 gene, which encodes MOX-1, is located on chromosome 17q21, underscoring its evolutionary conservation and significance across species.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MOX-1 Antibody (B-5) References:
- Mox2 is a component of the genetic hierarchy controlling limb muscle development. | Mankoo, BS., et al. 1999. Nature. 400: 69-73. PMID: 10403250
- Homeodomain proteins Mox1 and Mox2 associate with Pax1 and Pax3 transcription factors. | Stamataki, D., et al. 2001. FEBS Lett. 499: 274-8. PMID: 11423130
- Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. | Candia, AF., et al. 1992. Development. 116: 1123-36. PMID: 1363541
- Differential localization of Mox-1 and Mox-2 proteins indicates distinct roles during development. | Candia, AF. and Wright, CV. 1996. Int J Dev Biol. 40: 1179-84. PMID: 9032023
- The human homeobox genes MSX-1, MSX-2, and MOX-1 are differentially expressed in the dermis and epidermis in fetal and adult skin. | Stelnicki, EJ., et al. 1997. Differentiation. 62: 33-41. PMID: 9373945
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MOX-1 Antibody (B-5) | sc-398845 | 200 µg/ml | $316.00 | |||
MOX-1 Antibody (B-5): m-IgG Fc BP-HRP Bundle | sc-526328 | 200 µg Ab; 10 µg BP | $354.00 | |||
MOX-1 Antibody (B-5): m-IgG2a BP-HRP Bundle | sc-546586 | 200 µg Ab; 10 µg BP | $354.00 | |||
MOX-1 Antibody (B-5) X | sc-398845 X | 200 µg/0.1 ml | $316.00 | |||
MOX-1 Antibody (B-5) AC | sc-398845 AC | 500 µg/ml, 25% agarose | $416.00 | |||
MOX-1 Antibody (B-5) HRP | sc-398845 HRP | 200 µg/ml | $316.00 | |||
MOX-1 Antibody (B-5) FITC | sc-398845 FITC | 200 µg/ml | $330.00 | |||
MOX-1 Antibody (B-5) PE | sc-398845 PE | 200 µg/ml | $343.00 | |||
MOX-1 Antibody (B-5) Alexa Fluor® 488 | sc-398845 AF488 | 200 µg/ml | $357.00 | |||
MOX-1 Antibody (B-5) Alexa Fluor® 546 | sc-398845 AF546 | 200 µg/ml | $357.00 | |||
MOX-1 Antibody (B-5) Alexa Fluor® 594 | sc-398845 AF594 | 200 µg/ml | $357.00 | |||
MOX-1 Antibody (B-5) Alexa Fluor® 647 | sc-398845 AF647 | 200 µg/ml | $357.00 | |||
MOX-1 Antibody (B-5) Alexa Fluor® 680 | sc-398845 AF680 | 200 µg/ml | $357.00 | |||
MOX-1 Antibody (B-5) Alexa Fluor® 790 | sc-398845 AF790 | 200 µg/ml | $357.00 |