motilin Antibody (H-9): sc-376605
- motilin Antibody (H-9) is a mouse monoclonal IgG2b κ motilin antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1-115 representing full length motilin of human origin
- motilin Antibody (H-9) is recommended for detection of motilin of human origin by WB, IP, IF and ELISA
- Anti-motilin Antibody (H-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for motilin Antibody (H-9). This work is in progress.
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motilin Antibody (H-9) is a mouse monoclonal IgG2b kappa light chain antibody that detects motilin protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-motilin antibody (H-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Motilin, also referred to as MLN, is a 115 amino acid secreted peptide derived from the proteolytic cleavage of the promotilin precursor protein, which is essential for the production of motilin and motilin-associated peptide (MAP). This peptide is primarily located in the enteroendocrine cells of the small intestine, where motilin plays a crucial role in stimulating the rhythmic contractions of the gastrointestinal tract, particularly in the duodenum and colon. The regulation of these contractions is vital for proper digestive function, as motilin helps coordinate the movement of food through the digestive system during the interdigestive phase. The gene encoding motilin is situated on human chromosome 6, a region that comprises nearly 6% of the human genome and is associated with various health conditions, including early onset intestinal cancer and other genetic disorders. The presence of motilin and motilin′s interactions with specific receptors underscore motilin′s importance in gastrointestinal motility and overall digestive health, making motilin monoclonal antibody (H-9) an invaluable tool for researchers studying these processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
motilin Antibody (H-9) References:
- Receptor for motilin identified in the human gastrointestinal system. | Feighner, SD., et al. 1999. Science. 284: 2184-8. PMID: 10381885
- Ghrelin and motilin are cosecreted from a prominent endocrine cell population in the small intestine. | Wierup, N., et al. 2007. J Clin Endocrinol Metab. 92: 3573-81. PMID: 17595255
- Differences and significance of motilin, vasoactive intestinal peptide and gastrin in blood and gallbladder tissues of patients with gallstones. | Zhang, ZH., et al. 2008. Hepatobiliary Pancreat Dis Int. 7: 58-64. PMID: 18234640
- Absence of motilin gene mutations in infantile hypertrophic pyloric stenosis. | Svenningsson, A., et al. 2008. J Pediatr Surg. 43: 443-6. PMID: 18358279
- Sphincter of Oddi hypomotility and its relationship with duodenal-biliary reflux, plasma motilin and serum gastrin. | Zhang, ZH., et al. 2008. World J Gastroenterol. 14: 4077-81. PMID: 18609694
- Structure and expression of the human motilin gene. | Daikh, DI., et al. 1989. DNA. 8: 615-21. PMID: 2574660
- Sequence of an intestinal cDNA encoding human motilin precursor. | Seino, Y., et al. 1987. FEBS Lett. 223: 74-6. PMID: 3666144
- The motilin gene: subregional localisation, tissue expression, DNA polymorphisms and exclusion as a candidate gene for the HLA-associated immotile cilia syndrome. | Gasparini, P., et al. 1994. Hum Genet. 94: 671-4. PMID: 7989042
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
motilin Antibody (H-9) | sc-376605 | 200 µg/ml | $322.00 | |||
motilin Antibody (H-9) AC | sc-376605 AC | 500 µg/ml, 25% agarose | $424.00 | |||
motilin Antibody (H-9) HRP | sc-376605 HRP | 200 µg/ml | $322.00 | |||
motilin Antibody (H-9) FITC | sc-376605 FITC | 200 µg/ml | $336.00 | |||
motilin Antibody (H-9) PE | sc-376605 PE | 200 µg/ml | $349.00 | |||
motilin Antibody (H-9) Alexa Fluor® 488 | sc-376605 AF488 | 200 µg/ml | $364.00 | |||
motilin Antibody (H-9) Alexa Fluor® 546 | sc-376605 AF546 | 200 µg/ml | $364.00 | |||
motilin Antibody (H-9) Alexa Fluor® 594 | sc-376605 AF594 | 200 µg/ml | $364.00 | |||
motilin Antibody (H-9) Alexa Fluor® 647 | sc-376605 AF647 | 200 µg/ml | $364.00 | |||
motilin Antibody (H-9) Alexa Fluor® 680 | sc-376605 AF680 | 200 µg/ml | $364.00 | |||
motilin Antibody (H-9) Alexa Fluor® 790 | sc-376605 AF790 | 200 µg/ml | $364.00 |