MMP-11 Antibody (5#) is a mouse monoclonal IgG2b antibody that detects MMP-11 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). MMP-11, also known as stromelysin-3, plays a crucial role in the remodeling of the extracellular matrix, which is vital for processes such as tissue repair, embryogenesis, and tumor progression. MMP-11 is predominantly expressed in stromal cells of breast carcinomas, where MMP-11 contributes to the malignancy of epithelial cells by facilitating the degradation of extracellular matrix components, thereby promoting tumor invasion and metastasis. The regulation of MMP-11 is complex, as MMP-11 expression can be influenced by various factors including cytokines and growth factors, making MMP-11 an important target for understanding cancer biology and developing therapeutic strategies. Anti-MMP-11 antibody (5#) is an essential tool for researchers investigating the role of this enzyme in cancer progression and other pathological conditions.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MMP-11 Antibody (5#) | sc-517445 | 100 µg/ml | $316.00 |