MLN64 Antibody (B-2): sc-390039

MLN64 Antibody (B-2) is a mouse monoclonal IgG1 antibody that detects MLN64 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MLN64, also known as StARD3, plays a crucial role in cholesterol transport within cells, particularly in the late endosome, where MLN64 facilitates the movement of cholesterol to specific cytoplasmic receptor sites. This function helps regulate cholesterol levels, which are essential for maintaining cellular membrane integrity and signaling pathways. Dysregulation of cholesterol transport has been implicated in various diseases, including cancer, where MLN64 is often overexpressed in breast cancer cell lines and tissues, suggesting a potential role in tumor progression. MLN64 expression is predominantly cytoplasmic, with notable localization at condensation sites and perinuclear regions, as observed in immunofluorescence (IF) microscopy studies of breast cancer biopsies. Anti-MLN64 antibody (B-2) enables researchers to gain insights into MLN64′s involvement in cholesterol trafficking and cancer biology, making MLN64 (B-2) antibody a valuable tool for studies focused on lipid metabolism and oncogenesis.

The preferred MLN64 antibody is MLN64 Antibody (H-1): sc-166215.