MIP-3α Antibody (500-M28): sc-65368
- MIP-3α Antibody (500-M28) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against amino acids 27-96 of MIP-3α of human origin
- recommended for detection of MIP-3α of human origin by WB and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MIP-3α Antibody (500-M28). This work is in progress.
MIP-3α Antibody (500-M28) is a mouse monoclonal IgG1 light chain antibody that detects MIP-3α in human samples through applications such as western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). MIP-3α, a member of the C-C chemokine subfamily, plays a crucial role in immune responses by acting as a chemoattractant for lymphocytes and other immune cells, thereby facilitating their migration to sites of inflammation. MIP-3α is primarily expressed in various tissues, including the skin and lymphoid organs, which underscores MIP-3α′s involvement in both innate and adaptive immune responses. MIP-3α′s ability to recruit T cells and dendritic cells to areas of infection or injury highlights MIP-3α′s importance in orchestrating effective immune surveillance and response. Additionally, MIP-3α′s interactions with specific receptors, such as CCR6, are vital for mediating biological effects, making MIP-3α a key player in the regulation of immune cell trafficking. Anti-MIP-3α antibody (500-M28) serves as an essential tool for researchers studying the dynamics of immune responses and the underlying mechanisms of various inflammatory diseases.
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MIP-3α Antibody (500-M28) References:
- MIP-3alpha neutralizing monoclonal antibody protects against TNBS-induced colonic injury and inflammation in mice. | Katchar, K., et al. 2007. Am J Physiol Gastrointest Liver Physiol. 292: G1263-71. PMID: 17272517
- MIP-3alpha and MIP-1alpha rapidly mobilize dendritic cell precursors into the peripheral blood. | He, S., et al. 2008. J Leukoc Biol. 84: 1549-56. PMID: 18791167
- MIP-3α expression in macrophages is NOD dependent. | Hausmann, M., et al. 2012. Digestion. 85: 192-201. PMID: 22286692
- Microencapsulation of tumor lysates and live cell engineering with MIP-3α as an effective vaccine. | Huang, FY., et al. 2015. Biomaterials. 53: 554-65. PMID: 25890751
- MCP-1 and MIP-3α Secreted from Necrotic Cell-Treated Glioblastoma Cells Promote Migration/Infiltration of Microglia. | Jung, Y., et al. 2018. Cell Physiol Biochem. 48: 1332-1346. PMID: 30048972
- Expression and Purification of Chemokine MIP-3α (CCL20) through a Calmodulin-Fusion Protein System. | Ramamourthy, G., et al. 2019. Microorganisms. 7: PMID: 30626048
- A recombinant oncolytic Newcastle virus expressing MIP-3α promotes systemic antitumor immunity. | Huang, FY., et al. 2020. J Immunother Cancer. 8: PMID: 32759233
- Pleural cytokines MIF and MIP-3α as novel biomarkers for complicated parapneumonic effusions and empyema. | Yang, CY., et al. 2021. Sci Rep. 11: 1763. PMID: 33469074
- Decreased MIP-3α Production from Antigen-Activated PBMCs in Symptomatic HIV-Infected Subjects. | Zhang, F., et al. 2021. Pathogens. 11: PMID: 35055955
- A SARS-CoV-2 RBD vaccine fused to the chemokine MIP-3α elicits sustained murine antibody responses over 12 months and enhanced lung T-cell responses. | Gordy, JT., et al. 2024. Front Immunol. 15: 1292059. PMID: 38370404
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MIP-3α Antibody (500-M28) | sc-65368 | 100 µg/ml | $316.00 |