MIP-3α Antibody (4i165): sc-71585
- MIP-3α Antibody (4i165) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against amino acids 27-96 of MIP-3α of human origin
- recommended for detection of MIP-3α of human origin by WB and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MIP-3α Antibody (4i165). This work is in progress.
MIP-3α Antibody (4i165) is a mouse monoclonal IgG1 antibody that detects MIP-3α in human samples through applications such as western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). MIP-3α, also known as CCL20, plays a crucial role in the immune response by acting as a chemoattractant for lymphocytes and dendritic cells, particularly in the context of inflammation and immune surveillance. MIP-3α is primarily expressed in epithelial cells of various tissues, including the skin, gastrointestinal tract, and respiratory system, which facilitates the recruitment of immune cells to sites of infection or injury, thereby enhancing the body′s ability to respond to pathogens. MIP-3α′s ability to guide immune cells to specific locations underscores its importance in both innate and adaptive immunity, making MIP-3α a valuable target for research in immunology and potential therapeutic interventions. Anti-MIP-3α antibody (4i165) is an essential tool for scientists studying the dynamics of immune cell migration and the underlying mechanisms of inflammatory diseases.
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MIP-3α Antibody (4i165) References:
- Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: mechanism for modulating mucosal immunity. | Izadpanah, A., et al. 2001. Am J Physiol Gastrointest Liver Physiol. 280: G710-9. PMID: 11254498
- Neutrophils produce biologically active macrophage inflammatory protein-3alpha (MIP-3alpha)/CCL20 and MIP-3beta/CCL19. | Scapini, P., et al. 2001. Eur J Immunol. 31: 1981-8. PMID: 11449350
- Nasal polyp fibroblasts produce MIP-3alpha in response to toll-like receptor ligands and cytokine stimulation. | Nonaka, M., et al. 2010. Rhinology. 48: 41-6. PMID: 20502734
- Tumour regression induced by co-administration of MIP-3α and CpG in an experimental model of colon carcinoma. | Arab, S., et al. 2013. Scand J Immunol. 78: 28-34. PMID: 23672351
- Inflammatory Chemokines MIP-1δ and MIP-3α Are Involved in the Migration of Multipotent Mesenchymal Stromal Cells Induced by Hepatoma Cells. | Lejmi, E., et al. 2015. Stem Cells Dev. 24: 1223-35. PMID: 25579056
- Macrophage Inflammatory Protein-3 Alpha (MIP-3α)/CCL20 in HIV-1-Infected Individuals. | Aziz, N., et al. 2016. J AIDS Clin Res. 7: PMID: 27617163
- Serum concentrations of CCL20/MIP-3alpha in women with endometriosis. | Jabłoński, G., et al. 2019. Prz Menopauzalny. 18: 9-14. PMID: 31114452
- Immunotherapy combining tumor and endothelium cell lysis with immune enforcement by recombinant MIP-3α Newcastle disease virus in a vessel-targeting liposome enhances antitumor immunity. | Wang, JY., et al. 2022. J Immunother Cancer. 10: PMID: 35256516
- Cloning and characterization of a specific receptor for the novel CC chemokine MIP-3alpha from lung dendritic cells. | Power, CA., et al. 1997. J Exp Med. 186: 825-35. PMID: 9294137
- MIP-3alpha, MIP-3beta and fractalkine induce the locomotion and the mobilization of intracellular calcium, and activate the heterotrimeric G proteins in human natural killer cells. | Al-Aoukaty, A., et al. 1998. Immunology. 95: 618-24. PMID: 9893054
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MIP-3α Antibody (4i165) | sc-71585 | 100 µg/ml | $316.00 |