MIP-2 Antibody (RR14): sc-80193
- MIP-2 Antibody (RR14) is a rat monoclonal IgG2b provided at 100 µg/ml
- raised against full length recombinant MIP-2 of mouse origin
- recommended for detection of MIP-2 of mouse origin by WB and ELISA; non cross-reactive with MIP-1α, MIP-1β or GROα
- also provided azide-free for neutralization, sc-80193 L, 100 µg/0.1 ml
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MIP-2 Antibody (RR14). This work is in progress.
MIP-2 Antibody (RR14) is a rat monoclonal IgG2b antibody that detects MIP-2 in mouse samples through applications such as western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). MIP-2, also known as macrophage inflammatory protein-2, plays a crucial role in the immune response by acting as a potent chemoattractant for neutrophils and other immune cells, thereby facilitating their migration to sites of inflammation. This function is vital for the body′s defense mechanisms, as MIP-2 helps orchestrate the inflammatory response and promote tissue repair following injury or infection. MIP-2 is primarily secreted by activated macrophages and is involved in various pathological conditions, including autoimmune diseases and cancer, making MIP-2 an important target for therapeutic interventions. Anti-MIP-2 antibody (RR14) provides reliable detection and quantification of MIP-2, enabling researchers to explore its role in various biological processes and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MIP-2 Antibody (RR14) References:
- Neutralization of macrophage inflammatory protein 2 (MIP-2) and MIP-1alpha attenuates neutrophil recruitment in the central nervous system during experimental bacterial meningitis. | Diab, A., et al. 1999. Infect Immun. 67: 2590-601. PMID: 10225925
- MIP-2 secreted by epithelial cells increases neutrophil and lymphocyte recruitment in the mouse intestine. | Ohtsuka, Y., et al. 2001. Gut. 49: 526-33. PMID: 11559650
- Role for macrophage inflammatory protein 2 (MIP-2), MIP-1alpha, and interleukin-1alpha in the delayed-type hypersensitivity response to viral antigen. | Tumpey, TM., et al. 2002. J Virol. 76: 8050-7. PMID: 12134010
- Cadmium selectively induces MIP-2 and COX-2 through PTEN-mediated Akt activation in RAW264.7 cells. | Huang, YY., et al. 2014. Toxicol Sci. 138: 310-21. PMID: 24449419
- Autocrine control of MIP-2 secretion from metastatic breast cancer cells is mediated by CXCR2: a mechanism for possible resistance to CXCR2 antagonists. | Erin, N., et al. 2015. Breast Cancer Res Treat. 150: 57-69. PMID: 25682075
- MicroRNA-26a/-26b-COX-2-MIP-2 Loop Regulates Allergic Inflammation and Allergic Inflammation-promoted Enhanced Tumorigenic and Metastatic Potential of Cancer Cells. | Kwon, Y., et al. 2015. J Biol Chem. 290: 14245-66. PMID: 25907560
- Suppression of methylmercury-induced MIP-2 expression by N-acetyl-L-cysteine in murine RAW264.7 macrophage cell line. | David, J., et al. 2017. Eur J Med Res. 22: 45. PMID: 29122013
- 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates arthritic joints through reducing neutrophil infiltration mediated by IL-6/STAT3 and MIP-2 activation. | Kim, YJ., et al. 2017. Oncotarget. 8: 96636-96648. PMID: 29228558
- Inorganic mercury-induced MIP-2 expression is suppressed by N-acetyl-L-cysteine in RAW264.7 macrophages. | David, J., et al. 2020. Biomed Rep. 12: 39-45. PMID: 31929872
- Activation of MIP-2 and MCP-5 Expression in Methylmercury-Exposed Mice and Their Suppression by N-Acetyl-L-Cysteine. | Muniroh, M., et al. 2020. Neurotox Res. 37: 827-834. PMID: 32040762
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MIP-2 Antibody (RR14) | sc-80193 | 100 µg/ml | $316.00 | |||
MIP-2 Antibody (RR14) L | sc-80193 L | 100 µg/0.1 ml | $316.00 |