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Metaproterenol hemisulfate salt (CAS 5874-97-5)

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Application:
Metaproterenol hemisulfate salt is a β2-adrenoceptor agonist
CAS Number:
5874-97-5
Purity:
≥99%
Molecular Weight:
260.30
Molecular Formula:
C11H17NO305H2O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Metaproterenol hemisulfate salt is a synthetic sympathomimetic amine that acts as a beta-adrenergic agonist, specifically binding to the beta-2 adrenergic receptor (ADRB2). Its mechanism of action involves activating the G-protein coupled receptor, stimulating the production of cyclic adenosine monophosphate (cAMP), and subsequently triggering a range of downstream signaling pathways. In research, Metaproterenol hemisulfate salt has been employed as a tool to investigate the physiological and biochemical processes regulated by the beta-2 adrenergic receptor, including the modulation of smooth muscle tone, metabolic pathways, and gene expression. Its specific mechanism of action has provided valuable insights into the molecular mechanisms underlying cellular signaling and has been used to explain the role of the beta-2 adrenergic receptor in various physiological processes. Additionally, Metaproterenol hemisulfate salt has been utilized as a reference material in analytical chemistry, serving as a standard for the identification and quantification of beta-adrenergic agonists in various samples.


Metaproterenol hemisulfate salt (CAS 5874-97-5) References

  1. Bronchodilator responses to metaproterenol sulfate among subjects with spinal cord injury.  |  Schilero, GJ., et al. 2004. J Rehabil Res Dev. 41: 59-64. PMID: 15273898
  2. A comparison of the effects of ipratropium bromide and metaproterenol sulfate in acute exacerbations of COPD.  |  Karpel, JP., et al. 1990. Chest. 98: 835-9. PMID: 2145136
  3. Aerosol delivery of liposome metaproterenol sulfate.  |  McCalden, TA., et al. 1990. Proc West Pharmacol Soc. 33: 171-3. PMID: 2274531
  4. Combined inhalation of cromolyn sodium and metaproterenol sulfate in life-threatening asthma.  |  Rogers, JC. 1988. J Fam Pract. 26: 193-5. PMID: 3123591
  5. Effect of metaproterenol sulfate on mild asthmatics' response to sulfur dioxide exposure and exercise.  |  Linn, WS., et al. 1988. Arch Environ Health. 43: 399-406. PMID: 3196076
  6. Bronchodilator effects of some liposome formulations of metaproterenol sulfate in guinea pigs.  |  McCalden, TA., et al. 1988. Proc West Pharmacol Soc. 31: 129-32. PMID: 3211892
  7. A comparison of two delivery methods for aerosolized metaproterenol sulfate.  |  Salzman, GA. and Pyszczynski, DR. 1986. J Asthma. 23: 297-301. PMID: 3818510
  8. Albuterol protects against exercise-induced asthma longer than metaproterenol sulfate.  |  Berkowitz, R., et al. 1986. Pediatrics. 77: 173-8. PMID: 3945530
  9. Simple colorimetric method for determination of metaproterenol sulfate in pharmaceuticals.  |  Sane, RT., et al. 1984. J Assoc Off Anal Chem. 67: 137-8. PMID: 6698920
  10. Effect of aminophylline when added to metaproterenol sulfate and beclomethasone dipropionate aerosol.  |  Appel, DW. 1984. J Allergy Clin Immunol. 73: 291-7. PMID: 6699312
  11. Metaproterenol sulfate for asthmatic children with therapeutic serum theophylline concentrations.  |  Kelly, HW., et al. 1982. Clin Pharm. 1: 49-54. PMID: 6764162
  12. Bronchodilator effect of a new oral beta adrenoreceptor stimulant, Th1165a. A comparison with metaproterenol sulfate.  |  Geumei, AM., et al. 1976. Chest. 70: 460-5. PMID: 789024
  13. Evaluation of the effect of different fatty acids on the percutaneous absorption of metaproterenol sulfate.  |  Elyan, BM., et al. 1996. J Pharm Sci. 85: 101-5. PMID: 8926573

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Metaproterenol hemisulfate salt, 1 g

sc-257701
1 g
$600.00