MetAP-2 Antibody (G-5): sc-166826
- MetAP-2 Antibody (G-5) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 59-72 near the N-terminus of MetAP-2 of human origin
- recommended for detection of MetAP-2 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG2b BP-HRP is the preferred secondary detection reagent for MetAP-2 Antibody (G-5) for WB applications. This reagent is now offered in a bundle with MetAP-2 Antibody (G-5) (see ordering information below).
MetAP-2 Antibody (G-5) is a mouse monoclonal IgG2b antibody that detects methionine aminopeptidase 2 (MetAP-2) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MetAP-2 plays a crucial role in protein maturation by removing N-terminal methionine residues from nascent peptides, a process essential for proper folding and function of many proteins. MetAP-2 enzymatic activity regulates cell proliferation through control of various cellular processes, including cell cycle and apoptosis. MetAP-2 expression is tightly regulated, and MetAP-2 overexpression has been linked to several forms of cancer, making MetAP-2 a significant target for therapeutic intervention. Inhibitors of MetAP-2, such as ovalicin and fumagillin, have shown promise in cancer treatment by disrupting proliferation of NF1-associated tumors, highlighting MetAP-2′s importance in both normal physiology and disease states. MetAP-2 (G-5) antibody serves as an invaluable tool for researchers investigating MetAP-2′s role in cellular processes and cancer biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MetAP-2 Antibody (G-5) | sc-166826 | 200 µg/ml | $322.00 | |||
MetAP-2 Antibody (G-5): m-IgG2b BP-HRP Bundle | sc-548531 | 200 µg Ab; 10 µg BP | $361.00 | |||
MetAP-2 (G-5) Neutralizing Peptide | sc-166826 P | 100 µg/0.5 ml | $69.00 |