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MEK kinase-4 Antibody (E-5) is a mouse monoclonal IgG1 antibody that detects MEK kinase-4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MEK kinase-4 plays a crucial role in the mitogen-activated protein (MAP) kinase signaling cascade, which is essential for various cellular processes, including proliferation, differentiation, and response to stress. Specifically, MEK kinase-4 is known to activate the c-Jun N-terminal kinase (JNK) pathway, which is involved in regulating apoptosis and cellular responses to stress stimuli. The activation of this pathway is vital for maintaining cellular homeostasis and mediating the effects of growth factors and cytokines. By phosphorylating and activating JNK, MEK kinase-4 contributes to the cellular response to environmental changes, making MEK kinase-4 a key player in both normal physiological processes and pathological conditions such as cancer and neurodegenerative diseases. Anti-MEK kinase-4 antibody (E-5) is an invaluable tool for researchers aiming to explore the intricate signaling networks that govern cell behavior and to investigate the implications of MEK kinase-4 in various disease states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MEK kinase-4 Antibody (E-5) | sc-166196 | 200 µg/ml | $322.00 | |||
MEK kinase-4 Antibody (E-5): m-IgG1 BP-HRP Bundle | sc-542657 | 200 µg Ab; 20 µg BP | $361.00 |