MEF-2B Antibody (4B5): sc-517433
- MEF-2B Antibody (4B5) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 100 µg/ml
- raised against a recombinant protein corresponding to full length MEF-2B of human origin
- recommended for detection of MEF-2B of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MEF-2B Antibody (4B5). This work is in progress.
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MEF-2B Antibody (4B5) is a mouse monoclonal IgG2a light chain antibody that detects myocyte enhancer factor-2B (MEF-2B) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). MEF-2B plays a crucial role in regulating gene expression during muscle cell, neuronal cell, and T cell differentiation, making MEF-2B essential for proper development and function in these tissues. MEF-2B (4B5) antibody recognizes nuclear-localized MEF-2B, where MEF-2B acts as a transcription factor by binding to specific DNA sequences in target gene promoter regions. Nuclear localization of MEF-2B allows precise regulation of gene expression in response to various signaling pathways, critical for processes such as muscle development and repair. MEF-2B interacts with myogenic basic helix-loop-helix factors like MyoD and myogenin to form complexes that modulate muscle-specific gene transcription. MEF-2B forms homo- and heterodimers with other MEF-2 family members, enhancing regulatory capacity during cellular differentiation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MEF-2B Antibody (4B5) | sc-517433 | 100 µg/ml | $316.00 |