MCAT Antibody (3B5): sc-100477
- MCAT Antibody (3B5) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 50 µg/0.5 ml
- raised against recombinant MCAT of human origin
- recommended for detection of MCAT of human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MCAT Antibody (3B5). This work is in progress.
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SEE ALSO...
MCAT Antibody (3B5) is a mouse monoclonal IgG2a antibody that detects MCAT in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). MCAT, or mitochondrial malonyl CoA:ACP acyltransferase, plays a crucial role in lipid metabolism by catalyzing the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein, NDUFAB1, which is a vital component of respiratory complex I. This enzymatic activity is essential for initiating the type II fatty acid biosynthesis system, highlighting MCAT′s importance in maintaining cellular energy homeostasis and metabolic balance. MCAT is localized in the mitochondria, where MCAT is imported after being encoded by a nuclear gene, emphasizing the intricate interplay between nuclear and mitochondrial functions in cellular metabolism. Notably, MCAT exists in two isoforms due to alternative splicing, which may contribute to functional diversity and regulatory mechanisms within lipid biosynthesis pathways. Anti-MCAT antibody (3B5) serves as an invaluable tool for researchers investigating the complexities of fatty acid metabolism and mitochondrial function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MCAT Antibody (3B5) | sc-100477 | 50 µg/0.5 ml | $322.00 |