Marburg Virus Antibody (FM44): sc-52069
- Marburg Virus Antibody (FM44) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against purified and inactivated Marburg virus
- recommended for detection of high molecular weight material under non-reducing conditions and ~30K protein band under reducing conditions of Marburg Virus origin by WB (non-reducing)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Marburg Virus Antibody (FM44). This work is in progress.
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Marburg Virus Antibody (FM44) is a mouse monoclonal IgG1 antibody that detects Marburg Virus protein by western blotting (WB) under non-reducing conditions. Marburg Virus is a member of the Filoviridae family, notorious for long, threadlike particles ranging from 800 nm to 14,000 nm in length. This unique structure plays a significant role in evading host immune response and facilitating entry into host cells. The filamentous morphology allows for a larger surface area, enhancing interaction with host cell receptors and promoting efficient viral replication. Understanding Marburg Virus structure is vital for developing targeted therapies and vaccines, providing insights into viral operation and neutralization methods. Marburg Virus (FM44) monoclonal antibody serves as an essential tool for researchers studying this highly pathogenic virus, enabling exploration of viral mechanisms and host response to infection.
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Marburg Virus Antibody (FM44) References:
- Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA. | Thi, EP., et al. 2014. Sci Transl Med. 6: 250ra116. PMID: 25143366
- Ebola and Marburg virus vaccines. | Reynolds, P. and Marzi, A. 2017. Virus Genes. 53: 501-515. PMID: 28447193
- Vaccines against Ebola virus and Marburg virus: recent advances and promising candidates. | Suschak, JJ. and Schmaljohn, CS. 2019. Hum Vaccin Immunother. 15: 2359-2377. PMID: 31589088
- Marburg virus pathogenesis - differences and similarities in humans and animal models. | Shifflett, K. and Marzi, A. 2019. Virol J. 16: 165. PMID: 31888676
- Pathogenicity and virulence of Marburg virus. | Abir, MH., et al. 2022. Virulence. 13: 609-633. PMID: 35363588
- Comparison of Aerosol Stability of Different Variants of Ebola Virus and Marburg Virus and Virulence of Aerosolised Ebola Virus in an Immune-Deficient Mouse. | Smither, SJ., et al. 2022. Viruses. 14: PMID: 35458510
- Marburg Virus- A Threat During SARS-CoV-2 Era: A Review. | Ashique, S., et al. 2023. Infect Disord Drug Targets. 23: e280223214111. PMID: 36852815
- Transcriptomics of Marburg virus-infected primary proximal tubular cells reveals negative correlation of immune response and energy metabolism. | Koch, B., et al. 2024. Virus Res. 342: 199337. PMID: 38346476
- Recovery of Recombinant Marburg Virus by Reverse Genetics. | von Creytz, I. and Dolnik, O. 2025. Methods Mol Biol. 2877: 165-179. PMID: 39585621
- Genomic Evolution and Phylodynamics of the Species Orthomarburgvirus marburgense (Marburg and Ravn Viruses) to Understand Viral Adaptation and Marburg Virus Disease's Transmission Dynamics. | Muvunyi, CM., et al. 2024. Pathogens. 13: PMID: 39770366
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Marburg Virus Antibody (FM44) | sc-52069 | 100 µg/ml | $316.00 |