Marburg Virus Antibody (FM32): sc-52068
- Marburg Virus Antibody (FM32) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against purified and inactivated Marburg virus
- recommended for detection of high molecular weight material under non-reducing conditions and ~30K protein band under reducing conditions of Marburg Virus origin by WB (non-reducing)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Marburg Virus Antibody (FM32). This work is in progress.
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Marburg Virus Antibody (FM32) is a mouse monoclonal IgG1 antibody that detects Marburg Virus by western blotting (WB) under non-reducing conditions. Marburg Virus is a member of the Filoviridae family and is known for its long, threadlike particles that can range from 800 nm to 14,000 nm in length, which is crucial for its pathogenicity and ability to evade the host immune response. The structure of Marburg Virus plays a significant role in function, as the filamentous morphology allows for a larger surface area for interaction with host cells, facilitating entry and replication. This unique structure is also associated with Marburg Virus′s ability to induce severe hemorrhagic fever, characterized by high mortality rates and a range of debilitating symptoms, including high fever, diarrhea, and severe bleeding. Understanding the structural characteristics of Marburg Virus is essential for developing effective therapeutic strategies and vaccines, as these insights reveal how Marburg Virus interacts with host cells and eludes immune detection. Anti-Marburg Virus antibody (FM32) is an invaluable tool for researchers studying this highly lethal pathogen and its mechanisms of action.
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Marburg Virus Antibody (FM32) References:
- Crystal Structure of the Marburg Virus VP35 Oligomerization Domain. | Bruhn, JF., et al. 2017. J Virol. 91: PMID: 27847355
- Marburg virus-like particles produced in insect cells induce neutralizing antibodies in rhesus macaques. | Weiwei, G., et al. 2017. J Med Virol. 89: 2069-2074. PMID: 28402024
- Marburg virus regulates the IRE1/XBP1-dependent unfolded protein response to ensure efficient viral replication. | Rohde, C., et al. 2019. Emerg Microbes Infect. 8: 1300-1313. PMID: 31495285
- Prototype of a DNA Vaccine against Marburg Virus. | Volkova, NV., et al. 2021. Bull Exp Biol Med. 170: 475-478. PMID: 33713231
- They come in threes: Marburg virus, emerging infectious diseases, and the blood supply. | Jacobs, JW., et al. 2023. Transfus Apher Sci. 62: 103528. PMID: 36038475
- Development and optimization of biologically contained Marburg virus for high-throughput antiviral screening. | Vanmechelen, B., et al. 2022. Antiviral Res. 207: 105426. PMID: 36183903
- Deadly Marburg virus outbreak received sustained attention: What can we learn from the existing studies? | Cheng, K., et al. 2023. Int J Surg. 109: 2539-2541. PMID: 37204465
- Development of an Immunochromatography Assay to Detect Marburg Virus and Ravn Virus. | Changula, K., et al. 2023. Viruses. 15: PMID: 38140590
- Validation of Marburg Virus Inactivation by AVL Buffer. | Cutts, T., et al. 2025. Methods Mol Biol. 2877: 55-65. PMID: 39585613
- The Marburg virus outbreak of 1967 and subsequent episodes. | Slenczka, WG. 1999. Curr Top Microbiol Immunol. 235: 49-75. PMID: 9893378
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Marburg Virus Antibody (FM32) | sc-52068 | 100 µg/ml | $316.00 |