Marburg Virus Antibody (FM213): sc-52067
- Marburg Virus Antibody (FM213) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against purified and inactivated Marburg virus
- recommended for detection of high molecular weight material under non-reducing conditions and ~30K protein band under reducing conditions of Marburg Virus origin by WB (non-reducing)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Marburg Virus Antibody (FM213). This work is in progress.
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Marburg Virus Antibody (FM213) is a mouse monoclonal IgG1 antibody that detects Marburg Virus with species reactivity specific to Marburg Virus by western blotting (WB) under non-reducing conditions. Marburg Virus is a member of the Filoviridae family, notorious for long, threadlike particles ranging from 800 nm to 14,000 nm in length. The filamentous morphology allows for efficient entry into host cells and evasion of the immune response. Understanding Marburg Virus structural characteristics is essential for developing effective therapeutic strategies and vaccines, as these features influence host cell receptor interactions and viral assembly. Marburg Virus causes a severe and often fatal disease known as Marburg hemorrhagic fever, characterized by high fever, severe bleeding, and multi-organ failure, making structural and functional studies vital for public health and safety. Anti-Marburg Virus antibody (FM213) serves as an invaluable tool for researchers investigating this dangerous pathogen and its effects on human health.
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Marburg Virus Antibody (FM213) References:
- The glycoproteins of Marburg and Ebola virus and their potential roles in pathogenesis. | Feldmann, H., et al. 1999. Arch Virol Suppl. 15: 159-69. PMID: 10470276
- Recombinant vesicular stomatitis virus-based vaccines against Ebola and Marburg virus infections. | Geisbert, TW. and Feldmann, H. 2011. J Infect Dis. 204 Suppl 3: S1075-81. PMID: 21987744
- Compound FC-10696 Inhibits Egress of Marburg Virus. | Han, Z., et al. 2021. Antimicrob Agents Chemother. 65: e0008621. PMID: 33846137
- Marburg Virus Persistence on Fruit as a Plausible Route of Bat to Primate Filovirus Transmission. | Amman, BR., et al. 2021. Viruses. 13: PMID: 34960663
- Structural insight into Marburg virus nucleoprotein-RNA complex formation. | Fujita-Fujiharu, Y., et al. 2022. Nat Commun. 13: 1191. PMID: 35246537
- Mining of Marburg Virus Proteome for Designing an Epitope-Based Vaccine. | Soltan, MA., et al. 2022. Front Immunol. 13: 907481. PMID: 35911751
- Marburg Virus VP30 Is Required for Transcription Initiation at the Glycoprotein Gene. | Edwards, MR., et al. 2022. mBio. 13: e0224322. PMID: 35997284
- An introduction to the Marburg virus vaccine consortium, MARVAC. | Cross, RW., et al. 2022. PLoS Pathog. 18: e1010805. PMID: 36227853
- Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections. | Monteil, V., et al. 2023. Nat Commun. 14: 6785. PMID: 37880247
- Marburg virus exploits the Rab11-mediated endocytic pathway in viral-particle production. | Furuyama, W., et al. 2024. Microbiol Spectr. 12: e0026924. PMID: 39078193
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Marburg Virus Antibody (FM213) | sc-52067 | 100 µg/ml | $322.00 |