MAP-2 Antibody (A-8): sc-74422
- MAP-2 Antibody (A-8) is a mouse monoclonal IgG2a κ, cited in 13 publications, provided at 200 µg/ml
- raised against amino acids 1-300 of MAP-2 of human origin
- recommended for detection of MAP-2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See MAP-2 (A-4): sc-74421 for MAP-2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG2a BP-HRP is the preferred secondary detection reagent for MAP-2 Antibody (A-8) for WB and IHC(P) applications. This reagent is now offered in a bundle with MAP-2 Antibody (A-8) (see ordering information below).
MAP-2 Antibody (A-8) is a mouse monoclonal IgG2a antibody that detects MAP-2 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). MAP-2 is a crucial microtubule-associated protein that plays a significant role in stabilizing microtubules and facilitating their assembly, which is essential for maintaining the structural integrity of the cytoskeleton in neurons. MAP-2 is predominantly located in the dendrites of neurons, where MAP-2 contributes to the formation of dendritic spines and the overall architecture of the neuronal network. Proper localization of MAP-2 is vital for neuronal function, as MAP-2 influences synaptic plasticity and signal transduction pathways that are critical for learning and memory. Additionally, MAP-2 is subject to various post-translational modifications, including phosphorylation, which can modulate MAP-2′s activity and interactions with other proteins, further underscoring MAP-2′s importance in cellular dynamics and neurodevelopment. Anti-MAP-2 antibody (A-8) is an invaluable tool for researchers studying cytoskeletal dynamics and neuronal architecture, providing insights into the molecular mechanisms underlying neurodegenerative diseases and other neurological disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MAP-2 Antibody (A-8) | sc-74422 | 200 µg/ml | $322.00 | |||
MAP-2 Antibody (A-8): m-IgG2a BP-HRP Bundle | sc-546009 | 200 µg Ab; 10 µg BP | $361.00 |