MANSC1 Antibody (D-4): sc-514113

MANSC1 Antibody (D-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects MANSC1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MANSC1 (D-4) antibody is available as a non-conjugated antibody. MANSC1, also known as LOH12CR3 (Loss of heterozygosity 12 chromosomal region 3 protein), is a 414 amino acid single-pass membrane protein that plays a significant role in cellular processes. MANSC1 is expressed throughout various tissues in the body and is encoded by a gene located on chromosome 12, which is notable for its involvement in several genetic disorders, including skeletal deformities such as hypochondrogenesis and achondrogenesis. MANSC1′s structure, characterized by a MANSC domain, is crucial for cellular signaling and membrane interactions, which are essential for maintaining cellular homeostasis and responding to environmental stimuli. Understanding MANSC1′s role in these processes can provide insights into potential implications in developmental biology and disease mechanisms.

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MANSC1 Antibody (D-4) References:

1. The genomic context of natural killer receptor extended gene families.  |  Trowsdale, J., et al. 2001. Immunol Rev. 181: 20-38. PMID: 11513141
2. Mutational and expression analysis of the chromosome 12p candidate tumor suppressor genes in pre-B acute lymphoblastic leukemia.  |  Montpetit, A., et al. 2004. Leukemia. 18: 1499-504. PMID: 15284860
3. Genotype/phenotype analysis in a patient with pure and complete trisomy 12p.  |  Zumkeller, W., et al. 2004. Am J Med Genet A. 129A: 261-4. PMID: 15326625
4. The phenotypic spectrum of COL2A1 mutations.  |  Nishimura, G., et al. 2005. Hum Mutat. 26: 36-43. PMID: 15895462
5. Comparative genomics of natural killer cell receptor gene clusters.  |  Kelley, J., et al. 2005. PLoS Genet. 1: 129-39. PMID: 16132082
6. The natural history of trisomy 12p.  |  Segel, R., et al. 2006. Am J Med Genet A. 140: 695-703. PMID: 16502429
7. Cytogenetic and molecular analysis in trisomy 12p.  |  Allen, TL., et al. 1996. Am J Med Genet. 63: 250-6. PMID: 8723118
8. Low basal transcripts of the COL2A1 collagen gene from lymphoblasts show alternative splicing of exon 12 in the Kniest form of spondyloepiphyseal dysplasia.  |  Yang, W. and Cole, WG. 1998. Hum Mutat. Suppl 1: S1-2. PMID: 9452022

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-MANSC1 Antibody (D-4) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-MANSC1 Antibody (D-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

MANSC1 Antibody (D-4) Specifications

Alternate Product Name: MANSC1

Product Clone Name: D-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-140

Epitope Target: MANSC1

Epitope Species: human

Product Reactivity/Detection: MANSC1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for MANSC1 Antibody (D-4): N/A