The category termed MANSC1 Inhibitors represents a collection of compounds that, although not specifically targeting MANSC1, can exert influence on broader cellular processes or signaling pathways which MANSC1 might be associated with. These chemicals span diverse mechanisms, such as the disruption of the Golgi and vesicle trafficking by Brefeldin A, affecting proteins that rely on these processes for proper function or localization. Kinase inhibitors, such as Staurosporine and U0126, target broad kinase activities or specific pathways like MAPK, respectively. Proteins that are either regulated by or operate within these kinase pathways can be impacted by these inhibitors. The influence of inhibitors on protein synthesis and degradation, as evidenced by Cycloheximide and MG132, offers insight into modulating protein levels within the cellular milieu.
Furthermore, other inhibitors like 2-Deoxyglucose, which targets glycolysis, shed light on the intricate network of metabolic pathways and their impact on proteins associated with these processes. Through the understanding of these broader inhibitory methods and mechanisms, the implications on MANSC1, whether direct or indirect, provide valuable avenues for further probing its function, interactions, and regulatory mechanisms in cellular contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Brefeldin A can disrupt the Golgi apparatus and vesicle trafficking which, if associated with MANSC1, can indirectly affect its function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin inhibits PI3K, which is involved in numerous cellular processes. If MANSC1 is connected to a PI3K-mediated pathway, its function can be influenced. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor similar to Wortmannin. If MANSC1 functions within a PI3K-related pathway, its activity can be affected. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a broad-spectrum protein kinase inhibitor. Proteins sensitive to kinase-mediated signaling or processes can be affected. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
Another MEK inhibitor, affecting proteins associated with the MAPK pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
By inhibiting mTOR, Rapamycin can affect cell growth and autophagy processes. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Inhibits protein synthesis. If MANSC1 has a short half-life, its levels can be significantly reduced in the presence of this compound. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
A proteasome inhibitor. By affecting protein degradation, it can influence the stability and function of proteins. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
Interferes with glycolysis. If MANSC1 is linked to energy metabolism, its function can be impacted. | ||||||