Macrophage Marker Antibody (TE5): sc-73602

Macrophage Marker Antibody (TE5) is a mouse monoclonal IgG1 antibody that detects Macrophage Marker in human samples through immunofluorescence (IF) applications. Anti-Macrophage Marker antibody (TE5) plays a crucial role in identifying macrophages, which are essential components of the immune system, responsible for phagocytosing pathogens and debris, thus maintaining tissue homeostasis. Macrophages are strategically located in various tissues throughout the body, including the lungs, liver, and spleen, where they act as the first line of defense against infections. The presence of macrophages in these locations is vital, as they not only respond to pathogens but also facilitate tissue repair and modulate inflammatory responses. Macrophage Marker (TE5) antibody helps researchers gain insights into the dynamics of macrophage populations in different physiological and pathological contexts, enhancing our understanding of immune responses and potential therapeutic targets in diseases characterized by inflammation or immune dysregulation.

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Macrophage Marker Antibody (TE5) References:

1. LRP5: A novel anti-inflammatory macrophage marker that positively regulates migration and phagocytosis.  |  Ma, Y. 2016. J Mol Cell Cardiol. 91: 61-2. PMID: 26739212
2. F4/80 as a Major Macrophage Marker: The Case of the Peritoneum and Spleen.  |  Dos Anjos Cassado, A. 2017. Results Probl Cell Differ. 62: 161-179. PMID: 28455709
3. The macrophage marker translocator protein (TSPO) is down-regulated on pro-inflammatory 'M1' human macrophages.  |  Narayan, N., et al. 2017. PLoS One. 12: e0185767. PMID: 28968465
4. Peritoneal pre-conditioning reduces macrophage marker expression in collagen-containing engineered vascular grafts.  |  Shojaee, M., et al. 2017. Acta Biomater. 64: 80-93. PMID: 28987784
5. M2 Macrophage Marker Chitinase 3-Like 2 (CHI3L2) Associates With Progression of Conventional Renal Cell Carcinoma.  |  Pusztai, C., et al. 2019. Anticancer Res. 39: 6939-6943. PMID: 31810965
6. M2 macrophage marker CHI3L2 could serve as a potential prognostic and immunological biomarker in glioma by integrated single-cell and bulk RNA-Seq analysis.  |  Qian, W., et al. 2023. J Gene Med. 25: e3523. PMID: 37147894
7. Identification and validation of a novel signature based on macrophage marker genes for predicting prognosis and drug response in kidney renal clear cell carcinoma by integrated analysis of single cell and bulk RNA sequencing.  |  Chen, X., et al. 2024. Aging (Albany NY). 16: 5676-5702. PMID: 38517387
8. SFRP1 decreases WNT-Mediated M2 macrophage marker expression in breast tissue.  |  Gregory, KJ., et al. 2024. Cancer Immunol Immunother. 73: 86. PMID: 38554160
9. Bioinformatics Analysis Reveals Prognostic Significance of the Macrophage Marker Gene Signature in Gastric Adenocarcinoma.  |  Li, Z., et al. 2024. Front Biosci (Landmark Ed). 29: 172. PMID: 38812299
10. Identification of a Macrophage marker gene signature to evaluate immune infiltration and therapeutic response in hepatocellular carcinoma.  |  Li, T., et al. 2024. Heliyon. 10: e31881. PMID: 38845876

The preferred Macrophage Marker antibody is Macrophage Marker Antibody (MAC387): sc-66204.